Congenital absence of vas deferens and ectopic kidney

Abstract

HighlightsVery rare clinical entity.Large Association with multiple uro-genital malformation.Discovered usually by accident.Associated with infertility.

CFTR variants and renal abnormalities in males with congenital unilateral absence of the vas deferens (CUAVD): a systematic review and meta-analysis of observational studies

“…38 In fact, RA-associated CUAVD is due to an intrinsic defect in the Wolffian duct, as any defect or interruption before the complete separation of the Wolffian duct can lead to CUAVD combined with RA, whereas interruption after separation leads to isolated CUAVD. 52 Our conclusions further support these findings.…”

“…In 1737, John Hunter first described CAVD in a cadaver. 52 An association with renal agenesis has subsequently been noted. 4,14,53 We observed a high RA risk in CUAVD patients of 22%, which is around five times higher than that in CBAVD (5%).…”

“…Furthermore, delayed diagnosis of CUAVD can increase mortality and morbidity due to associated defects of the urogenital system. 52 Given the high frequency of RA risk in CUAVD, imaging of the urogenital system is strongly recommended in clinical practice to better evaluate patient general health and quality of life.…”

Vascular Abnormalities in a Pelvic Ectopic Kidney: How a Dissection-Based Program Improves the Knowledge of Clinical Anatomy

“…As ipsilateral absence of the vas deferens and ipsilateral undescended testis were reported earlier 5 associating ectopic pelvic kidneys, we dissected in the vicinity of the deep left internal ring looking for the vas deferens. We followed the vas deferens till it reached the prostate.…”

“…Moreover, it could be associated with other congenital defects such as undescended testis 4 and absence of vas deferens. 5…”