Congenital abdominal aortic aneurysm causing renovascular hypertension, cardiomyopathy, and death in a 19-day-old neonate

Postrenal biopsy AVM leading to severe hypertension and dilated cardiomyopathy

“…Dilated cardiomyopathy is seen only in the most severe form of hypertensive cardiomyopathy in those adult patients [4]. On the other hand, numerous case reports demonstrate that infants may present with heart failure secondary to renovascular hypertension with variable degrees of hypertensive cardiomyopathy [5][6][7][8], quite unlike the progressive pattern recognized in adults. In our patient, the LV had become significantly dilated, with markedly impaired systolic function, whereas normal wall thickness for age was maintained.…”

Large neonatal thoracoabdominal aneurysm: case report and review of the literature

“…Histopathologic analyses are available of 7 of the aneurysms [2,4,5,7,8,15,16]. They indicate clearly that congenital aneurysms are a heterogeneous group.…”

“…Gibson describes spontaneous rupture and death in a 16-month-old infant [2]. Two neonates with a juxtarenal aneurysm died of cardiac dysfunction before they could undergo surgery [7,16]. One aneurysm, measuring 3 cm in diameter, was allowed to run its natural course, and the infant was still alive after 2.5 years [17].…”

“…Reports of successful aneurysm resection have been published [2][3][4][5][6]. Timely diagnosis seems to be the key to successful treatment [7,8]. The case presented here shows that early diagnosis alone is not sufficient for a favorable outcome.…”

An infant with systemic hypertension, renal artery stenosis, and neuroblastoma

“…There are only a few individual case reports 4-9 describing severe, secondary hypertension in infancy and the newborn period and neonatal renovascular hypertension is multifactorial in etiology with causative lesions such as congenital neuroblastoma, 5 aortic aneurysm, 6 unilateral renal arterial disease, 7 hematoma within the renal arterial wall, 8 and complication of aortic monitoring catheters, 9 according to the literature. Neonatal neuroblastoma itself is a quite rare lesion, and constitutes 2.03% to 3.78% of all neuroblastomas.…”