“…13 C NMR (101 MHz, CDCl 3 ) δ 154.5, 145. 9,145.7,144.2,142.5,139.3,136.1,132.2,131.0,130.6,130.4,129.8,129.1,118.7,111.1. MS (EI,70 eV) 2'-(3,5'-Bis(trifluoromethyl)-[1,1'-biphenyl]-2-yl)pyrazine 13: Following general Procedure B using 2-phenylpyrazine (234 mg, 1.5 mmol) and 1-bromo-3,5-bis(trifluoromethyl)benzene (293 mg, 1 mmol), the residue was purified by flash chromatography on aluminium oxide (Heptane-EtOAc, 90-10) to afford the desired compound 13 (261 mg, 71 %) as a pale white solid (Mp = 134-136°C): 1 H NMR (400 MHz, CDCl 3 ) δ 8.53 (dd, J = 2.4, 1.6 Hz, 1H), 8.43 (d, J = 2.5 Hz, 1H), 8.30 (d, J = 1.3 Hz, 1H), 7.76 (s, 1H), 7.74-7.69 (m, 1H), 7.63 -7.57 (m, 4H), 7.54-7.49 (m, 1H).…”