Conformational Parameters of Poly(<i>N</i>‐methyl‐<i>N</i>‐vinylacetamide) Molecules Through the Hydrodynamic Characteristics Studies

Pavlov, G. G.; Okatova, O. V.; Mikhailova, A. V.; Ul’yanova, N. N.; Гаврилова, И. И.; Panarin, E. F.

doi:10.1002/mabi.200900475

Cited by 26 publications

(8 citation statements)

References 24 publications

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“…The matrix of the hydrodynamic data can be transformed into the matrix of molar masses and hydrodynamic invariants . The possibility of these transformations is conditioned by the fact that the experimental hydrodynamic values depend on mass and size of the macromolecule in a nonsimilar way (see eqs – and ). − , In the case of branched macromolecules the appropriate size characteristics is the mean-square radius of gyration of a macromolecule, ⟨ R 2 ⟩.…”

Section: Discussionmentioning

confidence: 99%

Star-Brush-Shaped Macromolecules: Peculiar Properties in Dilute Solution

2013

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Star-brush-shaped poly(ε-caprolactone)-blockpoly(oligo(ethylene glycol) methacrylate (PCL-b-POEGMA) macromolecules were synthesized and studied by molecular hydrodynamic methods. The values of the intrinsic viscosity, the velocity sedimentation coefficient, the translational diffusion coefficient, and the frictional ratio were obtained in acetone. Molar masses (M) were determined by the Svedberg relation, and the correlations between the hydrodynamic values and the molar mass were obtained in the range of 19 < M × 10 −3 g mol −1 < 124. Comparison of the scaling indexes of the intrinsic viscosity and sedimentation velocity coefficient versus molar mass corresponding to the conventional four-arm stars macromolecules with that of the star-brush-shaped copolymer macromolecules shows that the star-brush-shaped PCL-b-POEGMA macromolecules have the more dense organization in space which is connected with their different topology in contrast to the conventional stars macromolecules. The model of the PCL-b-POEGMA macromolecules based on the ensemble of their hydrodynamic characteristics is discussed.

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Section: Discussionmentioning

confidence: 99%

Star-Brush-Shaped Macromolecules: Peculiar Properties in Dilute Solution

2013

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“…The polymers were investigated earlier in water and salt-water solutions by the methods of molecular hydrodynamics: viscometry, sedimentation velocity, and translational diffusion. The results for poly-N-methyl-N-vinylacetamide (PMVA) are described in [ 57 ]; for hydroxypropylmethylcellulose (HPMC) in [ 58 ]; for PSSNa in [ 54 , 59 ]; for MVAA- co -MVAC n H 2n+1 in [ 55 , 60 , 61 ]. The copolymer bears charges at the junction of the main and each side chain.…”

Section: Methodsmentioning

confidence: 99%

New Facet in Viscometry of Charged Associating Polymer Systems in Dilute Solutions

et al. 2023

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The peculiarities of viscosity data treatment for two series of polymer systems exhibiting associative properties: brush-like amphiphilic copolymers—charged alkylated N-methyl-N-vinylacetamide and N-methyl-N-vinylamine copolymer (MVAA-co-МVACnH2n+1) and charged chains of sodium polystyrene-4-sulfonate (PSSNa) in large-scale molecular masses (MM) and in extreme-scale of the ionic strength of solutions were considered in this study. The interest in amphiphilic macromolecular systems is explained by the fact that they are considered as micellar-forming structures in aqueous solutions, and these structures are able to carry hydrophobic biologically active compounds. In the case of appearing the hydrophobic interactions, attention was paid to discussing convenient ways to extract the correct value of intrinsic viscosity from the combined analysis of Kraemer and Huggins plots, which were considered as twin plots. Systems and situations were demonstrated where intrachain hydrophobic interactions occurred. The obtained data were discussed in terms of vs. plots as well as in terms of normalized scaling relationships where was the relative viscosity of the polymer solution. The first plot allowed for the detection and calibration of hydrophobic interactions in polymer chains, while the second plot allowed for the monitoring of the change in the size of charged chains depending on the ionic strength of solutions.

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“…Color and symbol assignments of naturally-based macromolecules: Black-Rigid, Xanthan (squares) [25], Schizophyllan (triangles up) [28]; Blue-Semi-Flexible, Pectin (squares) [29,30], Chitosan (circles) [31,33,34], Chitin (triangles up) [35], Cellulose (triangles down) [12,[38][39][40][41]77], Heparin (diamonds) [42]; Green-Flexible, Mannan (circles) [45,78], Pullulan (triangles up) [46], Carrageenan (triangles down) [47]. Color and symbol assignments of synthetically-based macromolecules: Green-Flexible, Polyelectrolyte (squares), cationic [55,59,60], POx (triangles up) [13,65], amide containing vinyl copolymers (triangles down) [66,67], PEI (diamonds) [68], Polyvinylpyrrolidone (triangles left) [69]; Red-Branched, PEG copolymers (squares) [24].…”

Section: Recent Values For the Sedimentation Parameter β Smentioning

confidence: 99%

Incentives of Using the Hydrodynamic Invariant and Sedimentation Parameter for the Study of Naturally- and Synthetically-Based Macromolecules in Solution

et al. 2020

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The interrelation of experimental rotational and translational hydrodynamic friction data as a basis for the study of macromolecules in solution represents a useful attempt for the verification of hydrodynamic information. Such interrelation originates from the basic development of colloid and macromolecular science and has proven to be a powerful tool for the study of naturally- and synthetically-based, i.e., artificial, macromolecules. In this tutorial review, we introduce this very basic concept with a brief historical background, the governing physical principles, and guidelines for anyone making use of it. This is because very often data to determine such an interrelation are available and it only takes a set of simple equations for it to be established. We exemplify this with data collected over recent years, focused primarily on water-based macromolecular systems and with relevance for pharmaceutical applications. We conclude with future incentives and opportunities for verifying an advanced design and tailored properties of natural/synthetic macromolecular materials in a dispersed or dissolved manner, i.e., in solution. Particular importance for the here outlined concept emanates from the situation that the classical scaling relationships of Kuhn–Mark–Houwink–Sakurada, most frequently applied in macromolecular science, are fulfilled, once the hydrodynamic invariant and/or sedimentation parameter are established. However, the hydrodynamic invariant and sedimentation parameter concept do not require a series of molar masses for their establishment and can help in the verification of a sound estimation of molar mass values of macromolecules.

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Conformational Parameters of Poly(N‐methyl‐N‐vinylacetamide) Molecules Through the Hydrodynamic Characteristics Studies

Cited by 26 publications

References 24 publications

Star-Brush-Shaped Macromolecules: Peculiar Properties in Dilute Solution

Star-Brush-Shaped Macromolecules: Peculiar Properties in Dilute Solution

New Facet in Viscometry of Charged Associating Polymer Systems in Dilute Solutions

Incentives of Using the Hydrodynamic Invariant and Sedimentation Parameter for the Study of Naturally- and Synthetically-Based Macromolecules in Solution

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