Abstract:Deciphering chromatin regulation at the molecular level is of fundamental importance for an understanding of cellular physiological and pathological processes. Chromatin is an extremely complex system due to its molecular organization, heterogeneous structure and multiscale dynamics induced by post translational modifications on chromatin itself and other regulatory effectors including transcription factors (TFs). One key class of chromatin interacting proteins are pioneer transcription factors. The main chara… Show more
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