Conformational Analysis of 2,4-Disubstituted 9-Oxobicyclo[3.3.1]nonane Derivatives

Abstract

The conformational analysis of several 2,4-disubstituted 9-oxobicyclo[3.3.1]nonane derivatives (diesters IIIb and IIIc, and dihalo compounds IV, Va, Vb and VI) derived from 9-oxobicyclo[3.3.1]nonane-exo-2, exo-4-dicarboxylic acid has been studied by 1H and 13C NMR spectroscopy with the aid of Molecular Mechanics Calculations (MM3 program).