Conformational analysis of 12-crown-3 and sodium ion selectivity of electrodes based on bis(12-crown-3) derivatives with malonate spacers

A Cu2+ion-selective fluoroionophore with dual off/on switches

“…Disubstituted malonic acid dichloride was synthesized by the reaction of corresponding disubstituted malonic acids with (COCl) 2 in benzene [24]. Subsequently, the reaction of disubstituted malonic acid dichlorides with 1-pyrenylmethylamine hydrochloride in benzene gave a desired bispyrene 1 in 2% isolated yield.…”

Design of bisquinolinyl malonamides as Zn2+ ion-selective fluoroionophores based on the substituent effect

“…Malonic acid dichlorides were synthesized by the reaction of corresponding malonic acids with (COCl 2 ) in benzene or toluene. 6,7 Subsequently, the reaction of malonic acid dichlorides with 8-aminoquinoline in benzene or toluene resulted in the desired malonamides 2 -4. The fluorescence responses of the disubstituted malonamides 2 -4 were investigated in the absence or presence of 1 equiv.…”

“…6,[33][34][35] For the semi-empirical molecular orbital calculations of the free bisquinolinyl malonamides, the structure of malonamides having all four 8-quinolinyl N atoms directed inward towards the cavity was employed as the starting geometries. Calculations for free malonamides 1 -4 indicated that the dihedral angles between two quinoline rings varied according to the introduced substituents at the C2-position of the malonamides (Fig.…”

Supramolecular Based Membrane Sensors

“…The ion-selective electrode (ISE) based on di(1,5,9-trioxacyclododecanylmethyl) 2-dodecyl-2-methylmalonate had the highest selectivity for the sodium ion among the alkali and alkaline earths studied. The sodium ion selectivity of the ISE based on bis(12-crown-3) derivative was superior to that of the ISE based on the bis(12-crown-4) analogue [133]. …”