Conformational analysis of 1-oxaspiro [4.5] decanes

Conformation analysis. XXVI. Conformational equilibriums in 5,5-disubstituted 1,3-dioxanes

“…The results are shown in Table VII.69 Response ratios were determined at the same time and under the same conditions as the analyses. All equilibria were approached from both sides, that for the 5-hydroxy and 5-methyl-5-hydroxy (15,16) compounds also from the dioxolane side. Each sample was analyzed three to ten times using an F & M Model 810-19 or 810-29 dual thermal conductivity analytical research chromatograph equipped with a Honeywell Brown Elektronik Model 15 1.0-mV recorder and Disc Instrument Co. integrator.…”

“…2-Isopropyl-5-hydroxy-5-methyl-l,3-dioxanes (15,16). To a 500ml flask equipped with a magnetic stirrer containing a solution of 22.8 g (0.07 mol) of mercuric acetate in 70 ml of water and 70 ml of tetrahydrofuran was added, slowly and with cooling in an ice water bath, 9.9 g(0.07 mol) of 5-methylene-2-isopropyl-l,3-dioxane.…”