Conformal re-irradiation of recurrent head and neck tumors

Букша, А. Ю.; Гордон, Константин; Гулидов, И. А.; Рожнов, В. А.; Подлесных, Н. И.; Buksha, A. Yu.; Лепилина, О Г

doi:10.17116/onkolog20165254-57

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D Conformal Radiotherapy and Its Modifications1

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2023

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“…The original 3D conformal option has not been properly tested for reRT, which is a rather new clinical paradigm [50,51]. As the intensity-modulated modifications afford better distribution of the dose within irradiated volume, the original version is preserved mostly for comparative purposes.…”

Section: D Conformal Radiotherapy and Its Modificationsmentioning

confidence: 99%

An Overview of Head and Neck Tumor Reirradiation: What Has Been Achieved So Far?

Gordon,

Smyk,

Gulidov

et al. 2023

Cancers

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The recurrence rate of head and neck cancers (HNCs) after initial treatment may reach 70%, and poor prognosis is reported in most cases. Curative options for recurrent HNCs mainly depend on the treatment history and the recurrent tumor localization. Reirradiation for HNCs is effective and has been included in most guidelines. However, the option remains clinically challenging due to high incidence of severe toxicity, especially in cases of quick infield recurrence. Recent technical advances in radiation therapy (RT) provide the means for upgrade in reirradiation protocols. While the majority of hospitals stay focused on conventional and widely accessible modulated RTs, the particle therapy options emerge as tolerable and providing further treatment opportunities for recurrent HNCs. Still, the progress is impeded by high heterogeneity of the data and the lack of large-scale prospective studies. This review aimed to summarize the outcomes of reirradiation for HNCs in the clinical perspective.

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Section: D Conformal Radiotherapy and Its Modificationsmentioning

confidence: 99%