“…Published studies have detected C. pneumoniae in atherosclerosis arterial tissue using two different techniques such as polymerase chain reaction (PSR) and immunohistochemistry (IHC) but results are often difficult to interpret. (Cambell et al, 1995, Davidson et al, 1998 None of these techniques nowadays is perfect to detect the C. pneumoniae infection. There are long terms studies needed if we want to determine a potential role of C. Pneumoniae infection in the start of atherosclerosis plaque or only in arteriosclerosis progression Coronary artery disease being a specific form of atherosclerosis, is a very difficult case for studying.…”