Confirmed prevalence of food allergy and non‐allergic food hypersensitivity in a Mediterranean population

Gelincik, Aslı; Büyüköztürk, Suna; Gül, Hülya; Işık, Erol; İşsever, Halim; Özşeker, Ferhan; Çolakoğlu, Bahattin; Dal, Murat; Ayvaz, Özkan; Güngör, Günay; Akkor, A

doi:10.1111/j.1365-2222.2008.03019.x

Cited by 51 publications

(46 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In other studies on the prevalence of food allergy which used a questionnaire, Orhan et al (8) reported the prevalence to be 5.7% in 3500 school children aged between 6 and 9 in Eastern Black Sea region, Roehr et al (14) reported the prevalence to be 31.4% in 2354 children aged between 0 and 17 years in Germany and Osterballe et al (15) reported the prevalence to be 16.6% in individuals aged between 0 and 22 years. In these three studies, the prevalence was found to be 0.8%, 3.5% and 3.3%, respectivley after skin prick test and DBPCCT were performed (16). Differences may be determined between studies because of non-standard questions in questionnaire forms, inclusion of different age groups, different return rates of questionnaire forms and different consciousness and perception states of communities in terms of diseases.…”

Section: Discussionmentioning

confidence: 99%

“…Since there was an influenza epidemic (H5N1) in Samsun during the time when the study was performed and the families did not send their children to school because of the bias which developed in the community, return rates of the questionnaire forms handed out were lower than expected (53.5%). In the literature, return rates in survey studies are generally above 65% (8,16). A low return rate may decrease the strenght of the study to represent the population.…”

Section: Discussionmentioning

confidence: 99%

“…In a comprehensive study conducted in an adult age group in İstanbul, the rate of individuals who were thought to have FA was 9.5%, but the actual prevalence of FA was found to be only 0.1% (16). The most important cause for the variance was evaluated to be the varienace in the age groups included in the study.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of food allergy in nursery and kindergarten children in Samsun

Barlık¹,

Güner²,

Barlık³

et al. 2013

Turk Pediatri Ars

View full text Add to dashboard Cite

SummaryAim: In recent years, the frequency of food allergy in children has gradually increased. Food allergy affects growth, development and quality of life adversely. There is no enough research in the preschool age group in which food allergy is observed more frequently. In this study, we investigated the prevalence of food allergy in nursery and kindergarten children living in Samsun. Material and Method: Nursery and kindergarten children living in Samsun were included in this study. A standardized self-administered questionnaire on food allergy was handed out to 2390 parents. We achieved a response rate of 53.5%. The parents of children with suspected food allergy were called by phone to learn detailed history. Results: The prevalence of food allergy in nursery and kindergarten children in Samsun province was found to be 7.7% (99 subjects). 51.5% of 99 subjects who were found to have food allergy were male. There were no differences between the mean age of children with FA (5.03±1.0) and the healthy children (5.17± 0.86). The prevalence of FA in the three-year-old group was lower than the other age groups. The most common allergic foods were hen's egg (25.3%) and chocolate (21.2%), foods additives (1.2%), strawberry (9.2%), cow milk (7.1%) and nut (4.1%). The most commonly reported systemic reactions against foods were related with skin (53.5%) and gastrointestinal systems (31.4%). Conclusions: The prevalence of FA was similar to our country and the Asian countries, but lower than the European and American countries. In preschool children with recurrent skin and gastrointestinal tract symptoms, FA should be kept in mind. (Turk Arch Ped 2013; 48: 288-293)

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of food allergy in nursery and kindergarten children in Samsun

Barlık¹,

Güner²,

Barlık³

et al. 2013

Turk Pediatri Ars

View full text Add to dashboard Cite

show abstract

“…In adults, challenge-proven egg allergy data come from two studies, both reporting 0.1 % prevalence in Denmark (Osterballe et al, 2005) and Turkey (Gelincik et al, 2008). The same prevalence rate was reported in Germany for all ages combined based on clinical history and DBPCFC (Zuberbier et al, 2004).…”

Section: Introductionmentioning

confidence: 91%

Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes

Products¹

2014

EFS2

102

View full text Add to dashboard Cite

Following a request from the Food Safety Authority of Ireland, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA Panel) was asked to deliver a scientific opinion on the evaluation of allergenic foods and food ingredients for labelling purposes. In view of the request, the NDA Panel decided to update its previous opinions relative to food ingredients or substances with known allergenic potential listed in Annex IIIa of 2003/89/EC, as amended. These include cereals containing gluten, milk and dairy products, eggs, nuts, peanuts, soy, fish, crustaceans, molluscs, celery, lupin, sesame, mustard and sulphites. The opinion relates to immunoglobulin (Ig)E-and non-IgE-mediated food allergy, to coeliac disease and to adverse reactions to sulphites in food, and it does not address non-immune-mediated adverse reactions to food. It includes information on the prevalence of food allergy in unselected populations, proteins identified as food allergens, cross-reactivities, the effects of food processing on the allergenicity of foods and ingredients, methods for the detection of allergens and allergenic foods, doses observed to trigger adverse reactions in sensitive individuals and risk assessment methodologies that have been used to derive individual and population thresholds for selected allergenic foods. The present opinion relates to immunoglobulin (Ig)E-and non-IgE-mediated food allergy, to coeliac disease and to adverse reactions to sulphites in food, and it does not address non-immune-mediated adverse reactions to food. For each food ingredient or substance listed in Annex IIIa, it includes information on the prevalence of food allergy in unselected populations, on proteins identified as food allergens, on cross-reactivities, on the effects of food processing on the allergenicity of foods and ingredients, on methods for the detection of allergens and allergenic foods, and on doses observed to trigger adverse reactions in sensitive individuals.Immune-mediated adverse reactions to foods manifest with clinical signs and symptoms of variable severity and duration, which may affect different organs and systems. Anaphylactic reactions to food are IgE mediated and may occur at any age. Non-IgE-mediated food allergy includes a wide range of diseases, including protein-induced enterocolitis and eosinophilic oesophagitis.A careful family and clinical history are the basis for diagnosis of food allergy. Food diaries, skin prick tests (SPTs), allergen-specific IgE measurements, food elimination diets and food challenges are part of the standard protocol for the diagnosis of food allergy. A positive SPT indicates sensitisation to the tested food, but it is not diagnostic of food allergy. Allergen-specific serum IgE antibodies similarly denote sensitisation to a particular food, but they are not diagnostic without a clinical history or food challenge. The use of atopy patch tests for the diagnosis of food allergy is controversial. Other available tests have no current role in the diagnosis of food allergy. Diag...

show abstract

“…IgE aracılı reaksiyon şüphesinde şüpheli besin testten 10-14 gün önce, hücresel aracılı reaksiyonlarda (allerjik eozinofilik özefajit gibi) 8 hafta önce diyetten çıkarılmalıdır (6). Yükleme testleri, anafilaksi riski nedeniyle genellikle hastane ortamında (resüsitasyon ekipmanın hazır olduğu koşullarda) yapılır.…”

Section: Besin Yükleme Testiunclassified

Food Allergy

Mısırlıoğlu¹,

BOSTANCI²

2013

Turkish J Pediatr Dis

View full text Add to dashboard Cite

TaRİHÇEBesinlerin olumsuz reaksiyonlara yol açtığı 2000 yıldan uzun süredir bilinmektedir. Hipokrot'ın kayıtlarında inek sütüne karşı olan reaksiyonlardan söz edilmektedir. 1921'de Prausnitz ve Kustner ilk kez balık allerjisi reaksiyonunu tanımlamışlardır (1). EPİDEMİYoLoJİBesin allerjisi sıklığı yaş ve diyetle ilişkilidir (2). Hayatın ilk yıllarında daha fazladır. Hastalık önleme ve kontrol merkezi (CDC) 1997-2007 yılları arasında çocuklarda besin allerjisinin %18 oranında arttığını ve çocukların %3.9'unu etkilediğini bildirmiştir (3). Amerika Birleşik Devletlerinde ve ingiltere'de besin allerjileri tüm populasyonda %3.5-4 oranında, 5 yaş altında %6-8 oranında ve erişkinlerde %3'ün altında görülmektedir (1,2,4). Orta ve ağır atopik egzemada IgE aracılı besin allerjisi sıklığı %35 oranındadır (1). Ülkemizde besin allerjisi prevalansı konusunda net veri yoktur. Ancak çocuklarda besin allerjisi sıklığı giderek artmaktadır. Karadeniz bölgesinde 6-9 yaş arasındaki okul çocuklarında yapılan bir çalışmada anket ile besin allerjisi sıklığı %5.7 iken, çift kör plasebo kontrollü besin yükleme testinde %0.8 olarak saptanmıştır (5). istanbul'da yapılan bir çalışmada da çift kör plasebo kontrollü besin yükleme testi ile besin allerjisi sıklığı %0.1 olarak bulunmuştur (6). Erişkinlerle yapılan başka bir çalışmada ise besin allerjisi sıklığı %6.2 olarak bildirilmiştir (7). PATOGENEz bağırsak bariyeriGastrointestinal sistemin alınan besinlere karşı engelleri vardır. Gastrik asid ve pepsin, pankreatik ve intestinal enzimler, muküs, peristaltizm, bağırsak epitelinin bütünlüğü besin allerjenlerine karşı mekanik engellerdir. Bunun yanı sıra lenfoid doku, sekretuar IgA, CD8+ T hücreleri, makrofajların supressör ÖzETBesin allerjileri besinlere karşı istenmeyen immün yanıttır. Besin allerjileri ciddi ve hayatı tehdit eden reaksiyonlara yol açabilmektedir. Görülme sıklığı giderek artmaktadır. Besin alerjisi tanısında dikkatli öykü esastır. Basit tanı testlerinin rolü kısıtlıdır. Allerji veya toleransı göstermede besin yükleme testleri kullanılabilir. Tedavide allerjik reaksiyona neden olan besinden uzaklaşmak esastır. Gıda alımına bağlı allerjik bir reaksiyon geliştiğinde, tanı konulması, uygun tedavi ve yaklaşımda bulunulması önemlidir.Anahtar Sözcükler: Allerjen, Allerji, Anafilaksi, Besin, Çocuk ABSTrAcTFood allergy is an adverse immune response to food. It can cause severe and potentially life-threatening reactions. The prevalence of food allergy is increasing. A careful history is essential in the diagnosis of food allergy. The role of simple diagnostic tests is limited. An oral food challenge test can be used to confirm food allergy or tolerance. Treatment relies on avoidance of the food that triggers the allergic reaction. Early diagnosis, and an appropriate treatment and approach are very important when an allergic reaction develops due to food intake.

show abstract

Confirmed prevalence of food allergy and non‐allergic food hypersensitivity in a Mediterranean population

Cited by 51 publications

References 27 publications

Prevalence of food allergy in nursery and kindergarten children in Samsun

Prevalence of food allergy in nursery and kindergarten children in Samsun

Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes

Food Allergy

Contact Info

Product

Resources

About