Confidence intervals on intraclass correlation coefficients in a balanced two-factor random design

The Role of Centralized Reading of Endoscopy in a Randomized Controlled Trial of Mesalamine for Ulcerative Colitis

“…The resulting intraclass and interclass correlation coefficients (ICCs) are equivalent to a weighted k coefficient. Two-sided 95% CIs were obtained using the methods discussed by Gilder et al 22 Strength of agreement was evaluated according to the criteria of Landis and Koch whereby ICCs of <0.00, 0.00 to 0.20, 0.21 to 0.40, 0.41 to 0.60, 0.61 to 0.80, and 0.81 to 1.00 indicate poor, slight, fair, moderate, substantial, and almost perfect agreement, respectively. 23 The sample size calculation for the agreement study was based on the analysis of variance model.…”

Interobserver variability in assessing dysplasia and architecture in colorectal adenomas: a multicentre Canadian study

“…To determine the inter-rater and intra-rater reliability for both phases combined, the method of Gilder et al 33 was used. For the interpretation of the κ statistic, the cutoff values used in this study were: κ=0.21–0.40—fair agreement; κ=0.41–0.60—moderate agreement; κ=0.61–0.80—substantial agreement; κ=0.81–1.00, almost perfect agreement 34.…”

Variation in Clinical Target Volumes for Post-prostatectomy Patients and Effect on Normal Tissue Complication Probability

“…Inter-rater and intra-rater agreement with 95% confidence intervals were estimated simultaneously for the aforementioned volume, location, and shape variables using Gilder's method [19]. Gilder's method (aka modified large-sample approach) was used instead of other popular methods (e.g., DICE coefficients) because of more accurate coverage for both inter-and intra-rater reliability.…”