Confidence interval function analysis to evaluate the risk of mesothelioma among an expanded international cohort of cosmetic talc miners and millers

Marsh, Gary M.; Ierardi, A. Michael

doi:10.1016/j.yrtph.2020.104696

Cited by 9 publications

(3 citation statements)

References 28 publications

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“…For context, occupational epidemiology studies of highly exposed cosmetic talc miners and millers from Austria, France, Italy, Norway, and the U.S. (state of Vermont) demonstrated that these workers were not at an increased risk of mesothelioma (Finley et al, 2017; Garabrant and Pastula, 2018; Ierardi and Marsh, 2020; Ierardi et al, 2022; Marsh et al, 2019; Marsh and Ierardi, 2020). Zero cases of mesothelioma have been reported in all these cohorts except for the Vermont cosmetic talc miners and millers.…”

Section: Discussionmentioning

confidence: 99%

Occupational exposure to cosmetic talc and mesothelioma in barbers, hairdressers, and cosmetologists: A systematic review of the epidemiology

Lewis,

Smith,

Krevanko

et al. 2023

Toxicol Ind Health

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Inhalation exposure to cosmetic talc has generated much scientific debate regarding its potential as a risk factor for mesothelioma, a rare, but fatal cancer. Barbers, hairdressers, and cosmetologists have regularly used cosmetic talc-containing products, but the collective epidemiological evidence for mesothelioma in these occupations has yet to be described. As such, we conducted a systematic review of PubMed and the National Institute for Occupational Safety and Health’s (NIOSH) Numbered Publications list to identify original epidemiological literature reporting measures of association between these occupations and incidence of or death from mesothelioma. Literature screening was performed independently twice, the results of which were summarized and tabulated and underwent a review for their accuracy. A total of 12 studies met our inclusion criteria, including three cohort, six case–control, and three proportionate mortality/registration studies. The data from these studies were collected in 13 European and North American countries, spanning more than 50 years. We supplemented this review with queries of occupational mortality databases that are managed by the Washington State Department of Health and NIOSH for 26 U.S. states. Most findings were null and if statistically significant, nearly all showed an inverse relationship, indicative of a protective effect of these occupations on mesothelioma risk. Overall, the epidemiological evidence does not support an increased risk of mesothelioma for these occupations. This research fills an important data gap on the etiology of mesothelioma in barbers, hairdressers, and cosmetologists, and provides a benchmark for those with comparatively less exposure, such as non-occupational users of similar cosmetic talc-containing products.

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Section: Discussionmentioning

confidence: 99%

Occupational exposure to cosmetic talc and mesothelioma in barbers, hairdressers, and cosmetologists: A systematic review of the epidemiology

Lewis,

Smith,

Krevanko

et al. 2023

Toxicol Ind Health

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“…Before the previously referenced article by Moline et al, 1 the evidence was strongly against any mesothelioma risk from exposure to high-grade cosmetic talc. 2,3 The article by Moline et al, however, provided evidence of a possible mechanistic link between cosmetic talc exposure and mesothelioma by reporting the presence of asbestos fibers in tissue from six cosmetic talc-exposed individuals with mesothelioma who had no other apparent source of asbestos exposure. The implications of this were clear-cosmetic talc contained asbestos, an established cause of mesothelioma.…”

Section: Article By Moline Et Al Mesothelioma Associated With the Use...mentioning

confidence: 99%

Article by Moline et al. Mesothelioma Associated With the Use of Cosmetic Talc

Brent

2023

J Occup Environ Med

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“…Epidemiological studies of cosmetic talc miners and millers have found no discernible risk of mesothelioma and lung cancer (Boffetta et al., 2018; Coggiola et al., 2003; Finley et al., 2017; Fordyce et al., 2019; Ierardi & Marsh, 2020; Marsh & Ierardi, 2020; Pira et al., 2017; Rubino et al., 1976; Wergeland et al., 1990; Wild et al., 2002), suggesting no significant contamination of asbestos or other asbestiform minerals present in the mines and mills studied.…”

Section: Introductionmentioning

confidence: 99%

Characterization of asbestos exposures associated with the use of facial makeups

et al. 2022

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There has been renewed interest in the safety of cosmetics that may contain asbestos or other elongate mineral particles at very low levels as a naturally occurring contaminant. The authors evaluated asbestos exposure during the application of facial makeups in a constructed chamber simulating a bathroom space. The facial makeups tested included products previously found to have very low or “trace” asbestos content by governmental and commercial laboratories using a variety of bulk analysis methods. Tremolite asbestos was detected in five of 54 personal air samples and three of 72 area air samples in 18 simulations. The calculated geometric mean and 95th percentile task‐based asbestos concentration associated with personal facial makeup use in this study, incorporating censored data, is 0.0015 and 0.0018 fiber per cubic centimeter (f/cc), respectively, with a corresponding 95th percentile 24‐h time‐weighted average (TWA) asbestos concentration of 0.00008 f/cc for three applications per day in a simulated bathroom with no active ventilation. Based on these results, cumulative non‐occupational asbestos exposures confer a less than one in 1,000,000 risk of asbestos‐related disease based on many typical usage patterns and less than 1/100,000 risk with upper‐end lifetime usage patterns, using the US Environmental Protection Agency asbestos risk model.

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Confidence interval function analysis to evaluate the risk of mesothelioma among an expanded international cohort of cosmetic talc miners and millers

Cited by 9 publications

References 28 publications

Occupational exposure to cosmetic talc and mesothelioma in barbers, hairdressers, and cosmetologists: A systematic review of the epidemiology

Occupational exposure to cosmetic talc and mesothelioma in barbers, hairdressers, and cosmetologists: A systematic review of the epidemiology

Article by Moline et al. Mesothelioma Associated With the Use of Cosmetic Talc

Characterization of asbestos exposures associated with the use of facial makeups

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