Conduritol F, the discriminant marker between C. wilfordii and C. auriculatum by 1H NMR spectroscopy

Jang, Hyeon Seok; Jeong, Birang; Choi, Seong Yeon; Jang, Gyu Ho; Park, Kyong Cheul; Kwon, Yong Soo; Yang, Heejung

doi:10.1016/j.microc.2017.09.001

Cited by 5 publications

(12 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The qNMR experiments were conducted on a Bruker Avance III instrument operating at 500 MHz for 19 F at room temperature (about 298 K) using the parameters including pulse sequence of zg30, number of scans (NS) of 200 times, pulse width (P1) of 13.9 s, relaxation delay (D1) of 1 s, and acquisition time (aq) of 0.35 s. Signals of the samples were sensitive, and the relaxation delay and acquisition time were sufficient for relaxation of protons. 19 F NMR data were processed by the MestReNova software (Mestrelab Research, S.L. ), and baseline of each spectrum was corrected using the Whittaker Smoother routine included in the MestReNova software.…”

Section: Methodsmentioning

confidence: 99%

“…As a powerful and versatile technique to enable the absolute quantification of specific components in a mixture with excellent reproducibility, qNMR is also used to determine the purity of the samples by comparison with an internal standard (IS) . It was an alternative analytical method for the identification and discrimination of polyphenol and phosphatide by NMR spectroscopy . The qNMR was also applied for the determination of epigoitrin in Radix isatidis .…”

Section: Introductionmentioning

confidence: 99%

“…18 It was an alternative analytical method for the identification and discrimination of polyphenol and phosphatide by NMR spectroscopy. 19 The qNMR was also applied for the determination of epigoitrin in Radix isatidis. 20 Moreover, no calibration curve is needed for quantitative analysis when using the qNMR method and thus no specific pure reference standard is required.…”

Section: Introductionmentioning

confidence: 99%

“…28 Ab initio method has been extensively used to calculate the chemical properties, such as NMR and infrared. 29 Molecular modeling was conducted as a part of this study to elucidate the mechanism of SF 6 loaded in γ-CD-MOF with evidence that significant differences in the 19 F NMR spectra were generated by SF 6 in varied molecular environment.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Molecular Mechanism of Loading Sulfur Hexafluoride in γ-Cyclodextrin Metal–Organic Framework

Han

Guo

et al. 2018

J. Phys. Chem. B

View full text Add to dashboard Cite

γ-Cyclodextrin metal-organic framework (γ-CD-MOF) is a new type of highly porous carrier for potential loading of therapeutic or diagnostic gas like sulfur hexafluoride (SF). Here, loading of SF into γ-CD-MOF was investigated for its mechanism by molecular simulation and quantitative determination of SF using quantitative nuclear magnetic resonance (qNMR). For the SF loading, γ-CD-MOF was first degassed to remove the air without thermal decomposition or loss of framework crystallinity, then placed in the copper tube, and sealed to adsorb SF under 1.2 MPa and 25 °C for 12 h. The qNMR was employed for the determination of SF loaded in γ-CD-MOF using Span 80 as suspending agent and trifluoroacetic acid as internal standard. Then, the thermodynamic parameters had been estimated. Finally, molecular modeling combining with F NMR spectra was conducted to reveal the status of SF molecules in γ-CD-MOF. The results demonstrated that the content of SF loaded in γ-CD-MOF was 2.67 ± 0.46 wt %. After exposing to the environment of free SF at 0.1 MPa for 10 days, the relative content was 74.7%. It was confirmed that SF preferred to stay in the cavity of γ-CD-MOF cubes rather than in the γ-CD molecular pairs, which was a nonchemical adsorptive process. In conclusion, this research has established qNMR method and molecular simulation to demonstrate SF molecules in γ-CD-MOF and its loading mechanism.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Molecular Mechanism of Loading Sulfur Hexafluoride in γ-Cyclodextrin Metal–Organic Framework

Han

Guo

et al. 2018

J. Phys. Chem. B

View full text Add to dashboard Cite

show abstract

“…For example, in the genus of Cynanchum , axasterol acetate, metaplexigenin, and stigmasterol were only isolated from CA , suggesting they could be recognized as chemotaxonomic markers to differentiate CA and the other two species [ 13 ]. Equally, a study revealed that conduritol F had the potential to be developed into a chemical marker to distinguish CA and CW , evidenced by its H-5 and H-6 signals being well-separated from other signals by the analysis of quantitative NMR [ 14 ]. It is noteworthy that alkaloids isolated from three species were all from CA , which could be used as chemical markers to distinguish CA from the other two species [ 13 , 15 , 16 ].…”

Section: Botanymentioning

confidence: 99%

Cynanchum auriculatum Royle ex Wight., Cynanchum bungei Decne. and Cynanchum wilfordii (Maxim.) Hemsl.: Current Research and Prospects

et al. 2021

View full text Add to dashboard Cite

Cynanchum auriculatum Royle ex Wight. (CA), Cynanchum bungei Decne. (CB) and Cynanchum wilfordii (Maxim.) Hemsl. (CW) are three close species belonging to the Asclepiadaceous family, and their dry roots as the bioactive part have been revealed to exhibit anti-tumor, neuroprotection, organ protection, reducing liver lipid and blood lipid, immunomodulatory, anti-inflammatory, and other activities. Until 2021, phytochemistry investigations have uncovered 232 compounds isolated from three species, which could be classified into C21-steroids, acetophenones, terpenoids, and alkaloids. In this review, the morphology characteristics, species identification, and the relationship of botany, extraction, and the separation of chemical constituents, along with the molecular mechanism and pharmacokinetics of bioactive constituents of three species, are summarized for the first time, and their phytochemistry, pharmacology, and clinical safety are also updated. Moreover, the direction and limitation of current research on three species is also discussed.

show abstract

Establishment of adventitious root culture system of Cynanchum wilfordii in air-lift bioreactors for the efficient production of bioactive compounds

Wang¹,

Wang²,

An³

et al. 2022

In Vitro Cell.Dev.Biol.-Plant

View full text Add to dashboard Cite

Conduritol F, the discriminant marker between C. wilfordii and C. auriculatum by 1H NMR spectroscopy

Cited by 5 publications

References 13 publications

Molecular Mechanism of Loading Sulfur Hexafluoride in γ-Cyclodextrin Metal–Organic Framework

Molecular Mechanism of Loading Sulfur Hexafluoride in γ-Cyclodextrin Metal–Organic Framework

Cynanchum auriculatum Royle ex Wight., Cynanchum bungei Decne. and Cynanchum wilfordii (Maxim.) Hemsl.: Current Research and Prospects

Establishment of adventitious root culture system of Cynanchum wilfordii in air-lift bioreactors for the efficient production of bioactive compounds

Contact Info

Product

Resources

About