Conductive polyelectrolyte multilayers PANI membranes synthesis for tunable filtration ranges

Yusoff, Izzati Izni; Rohani, Rosiah; Ng, Law Yong; Mohammad, Abdul Wahab

doi:10.1007/s10853-019-03779-z

Cited by 20 publications

(11 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9A,B). Furthermore, the DLS studies confirmed the absence of aggregates, which could be due to increased hydrophilicity on acidic doping showing the same behavior as reported earlier 45 . This could be advantageous because it allows the TANI segment to express full antioxidant potential compared to the reduced segment due to the internal core.…”

Section: Critical Micelle Concentration (Cmc)supporting

confidence: 86%

A unique amphiphilic triblock copolymer, nontoxic to human blood and potential supramolecular drug delivery system for dexamethasone

Mushtaq

Akhter

Farooq

et al. 2021

Sci Rep

View full text Add to dashboard Cite

The drug delivery system (DDS) often causes toxicity, triggering undesired cellular injuries. Thus, developing supramolecules used as DDS with tunable self-assembly and nontoxic behavior is highly desired. To address this, we aimed to develop a tunable amphiphilic ABA-type triblock copolymer that is nontoxic to human blood cells but also capable of self-assembling, binding and releasing the clinically used drug dexamethasone. We synthesized an ABA-type amphiphilic triblock copolymer (P2L) by incorporating tetra(aniline) TANI as a hydrophobic and redox active segment along with monomethoxy end-capped polyethylene glycol (mPEG2k; Mw = 2000 g mol−1) as biocompatible, flexible and hydrophilic part. Cell cytotoxicity was measured in whole human blood in vitro and lung cancer cells. Polymer-drug interactions were investigated by UV–Vis spectroscopy and computational analysis. Our synthesized copolymer P2L exhibited tuned self-assembly behavior with and without external stimuli and showed no toxicity in human blood samples. Computational analysis showed that P2L can encapsulate the clinically used drug dexamethasone and that drug uptake or release can also be triggered under oxidation or low pH conditions. In conclusion, copolymer P2L is nontoxic to human blood cells with the potential to carry and release anticancer/anti-inflammatory drug dexamethasone. These findings may open up further investigations into implantable drug delivery systems/devices with precise drug administration and controlled release at specific locations.

show abstract

Section: Critical Micelle Concentration (Cmc)supporting

confidence: 86%

A unique amphiphilic triblock copolymer, nontoxic to human blood and potential supramolecular drug delivery system for dexamethasone

Mushtaq

Akhter

Farooq

et al. 2021

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Polyaniline (PANI) is a semi-flexible conducting polymer of the organic semiconductor family [4], which has attracted intensive interest as a result of remarkable features including superior conductivity [5], environmental stability [6], intriguing redox process [7] and inexpensive starting material [8]. In multidisciplinary areas, various applications for PANI have been reported such as biosensors, supercapacitors, biofuel cells, actuators, corrosion protection, membranes, solar cell devices, and rechargeable batteries [4,[9][10][11][12]. Tunable properties, good processability (facile synthesis process), affordability, suitable electrochemical and environmental stability, strong bimolecular interactions and intriguing acid/base and doping/dedoping properties have made PANI a promising polymer among inherently conducting polymers [10].…”

Section: Introductionmentioning

confidence: 99%

A highly sensitive biosensor based on methacrylated graphene oxide-grafted polyaniline for ascorbic acid determination

Naghib

Behzad

Rahmanian

et al. 2020

Nanotechnology Reviews

View full text Add to dashboard Cite

Functionalized graphene-based nanocomposites have opened new windows to address some challenges for increasing the sensitivity, accuracy and functionality of biosensors. Polyaniline (PANI) is one of the most potentially promising and technologically important conducting polymers, which brings together the electrical features of metals with intriguing properties of plastics including facile processing and controllable chemical and physical properties. PANI/graphene nanocomposites have attracted intense interest in various fields due to unique physicochemical properties including high conductivity, facile preparation and intriguing redox behavior. In this article, a functionalized graphene-grafted nanostructured PANI nanocomposite was applied for determining the ascorbic acid (AA) level. A significant current response was observed after treating the electrode surface with methacrylated graphene oxide (MeGO)/PANI nanocomposite. The amperometric responses showed a robust linear range of 8–5,000 µM and detection limit of 2 µM (N = 5). Excellent sensor selectivity was demonstrated in the presence of electroactive components interfering species, commonly found in real serum samples. This sensor is a promising candidate for rapid and selective determination of AA.

show abstract

“…During the stress-strain testing, the samples appeared to be noticeably elongated before breaking. The samples were mostly distinguished by their high elasticity and ductility in comparison with PANI, which is known to be a brittle material [24,25].…”

Section: Discussionmentioning

confidence: 99%

Highly Flexible Polyaniline-Based Implantable Electrode Materials for Neural Sensing/Stimulation Applications

Almufleh

Al‐Othman

Alani

et al. 2021

Electronic Materials

View full text Add to dashboard Cite

Implantable bioelectrodes have the potential to advance neural sensing and muscle stimulation, mainly in patients with peripheral nerve injuries. They function as the transducer at the interface between the damaged nerve and the muscle which is controlled by that nerve. This work reports the fabrication and characterization of novel, low-cost, flexible bioelectrodes based on polyaniline (PANI) and supported with silicone polymer. The fabricated electrodes were evaluated for their electrical and mechanical characteristics. PANI was used as the main transducer component in this fabrication. The characterization methods included electrical conductivity, capacitive behavior, long-term electrical impedance, and mechanical evaluation. The results of the fabricated PANI-silicone-based samples displayed a bulk impedance of 0.6 kΩ with an impedance of 1.6 kΩ at the frequency of 1 kHz. Furthermore, the bioelectrodes showed a charge storage capacity range from 0.0730 to 4.3124 C/cm2. The samples were stable when subjected to cyclic voltammetry tests. The bioelectrodes revealed very flexible mechanical properties as observed from the value of Young’s modulus (in the order of MPa) which was less than that of skin. Hence, the PANI-based bioelectrodes reported herein showed promising electrochemical characteristics with high flexibility.

show abstract

Conductive polyelectrolyte multilayers PANI membranes synthesis for tunable filtration ranges

Cited by 20 publications

References 55 publications

A unique amphiphilic triblock copolymer, nontoxic to human blood and potential supramolecular drug delivery system for dexamethasone

A unique amphiphilic triblock copolymer, nontoxic to human blood and potential supramolecular drug delivery system for dexamethasone

A highly sensitive biosensor based on methacrylated graphene oxide-grafted polyaniline for ascorbic acid determination

Highly Flexible Polyaniline-Based Implantable Electrode Materials for Neural Sensing/Stimulation Applications

Contact Info

Product

Resources

About