Conduct disorder among adolescent alcohol and drug abusers.

Brown, Sandra A.; Gleghorn, Alice; Schuckit, Marc A.; Myers, Mark G.; Mott, Mariam A.

doi:10.15288/jsa.1996.57.314

Cited by 194 publications

(131 citation statements)

References 27 publications

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“…Keeping in mind that we restricted the data analysis to a limited number of psychosocial factors, our study is consistent with other studies suggesting that youth with externalizing disorders (deviant behavior), that continue to affiliate with drug-using peers, and that have non-cohesive families are more likely to show a poorer course following treatment (e.g., [76][77][78]. Thus, relapse prevention strategies aimed at correcting risk associated with delinquency, peer drug use and family estrangement command attention in treatment.…”

Section: Discussionsupporting

confidence: 86%

Interplay of Psychosocial Factors and the Long-Term Course of Adolescents with a Substance Use Disorder

et al. 2008

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This paper examines the association of psychosocial factors and long-term drug use behaviors (year-5.5) among adolescents with a substance dependence disorder. One group received treatment with a 12-Step approach (n = 159) and one group was on a waiting list (n = 62). Four psychosocial factors (deviant behavior, peer drug environment, psychological disturbance and family estrangement), as measured by a standardized self-report questionnaire, were examined as predictors across three time points (year-1, year-4 and year-5.5). Improved outcome across time was significantly associated with decreases in deviant behavior, peer drug environment and family estrangement. However, psychological disturbance was not associated with outcome. Also, we did not find an effect on outcome as a function of age, gender and race. Youth that received treatment, as opposed to the waiting list youth, generally revealed a more favorable outcome across time. Treatment implications of the study findings are discussed.

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Section: Discussionsupporting

confidence: 86%

Interplay of Psychosocial Factors and the Long-Term Course of Adolescents with a Substance Use Disorder

et al. 2008

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“…As noted in the introduction, several studies have shown the prognostic significance of co-occurring conduct disorder for drug-abusing youth (Brown, Gleghorn, Schuckit, Myers, & Mott, 1996;Crowley et al, 1998;Myers et al, 1995;Tomlinson, Brown, & Abrantes, 2004). An additional contribution of this study to this comorbidity literature is that our follow-up period is longer than the more typical shorter term follow-up periods in the literature, and we included a community-based control group.…”

Section: Discussionmentioning

confidence: 99%

Internalizing and externalizing behaviors and their association with the treatment of adolescents with substance use disorder

Winters

Stinchfield

Latimer

et al. 2008

Journal of Substance Abuse Treatment

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“…Because of high comorbidity with substance use disorders (Brown, Gleghorn, Schuckit, Myers, & Mott, 1996;, teens meeting criteria for conduct disorder (n=2) were not excluded. Overall, 9% of the 729 youths who responded to the flyer met eligibility criteria for the study, and most ineligibilities were due to psychiatric symptomatology, other drug involvement, or braces.…”

Section: Authorsmentioning

confidence: 99%

Blood Oxygen Level Dependent Response and Spatial Working Memory in Adolescents With Alcohol Use Disorders

Tapert

Schweinsburg

Barlett

et al. 2004

Alcoholism Clin & Exp Res

195

194

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Background: Previous studies have suggested neural disruption and reorganization in young and older adults with alcohol use disorders (AUD). However, it remains unclear at what age and when in the progression of AUD changes in brain functioning might occur. Methods: Alcohol use disordered (n=15) and nonabusing (n=19) males and females ages 15-17 were recruited from local high schools. Functional magnetic resonance imaging (fMRI) data were collected after a minimum of 5 days' abstinence as participants performed spatial working memory and simple motor tasks. Results: Adolescents with AUD showed greater brain response to the spatial working memory task in bilateral parietal cortices, and diminished response in other regions including the left precentral gyrus and bilateral cerebellar areas (clusters ≥ 943 μl, p < .05), although groups did not differ on behavioral measures of task performance. No brain response differences were observed during a simple finger tapping task. The degree of abnormality was greater for teens who reported experiencing more withdrawal or hangover symptoms, and who consumed more alcohol. Conclusions: Adolescents with AUD show abnormalities in brain response to a spatial working memory task, despite adequate performance, suggesting that subtle neuronal reorganization may occur early in the course of AUD.

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Conduct disorder among adolescent alcohol and drug abusers.

Cited by 194 publications

References 27 publications

Interplay of Psychosocial Factors and the Long-Term Course of Adolescents with a Substance Use Disorder

Interplay of Psychosocial Factors and the Long-Term Course of Adolescents with a Substance Use Disorder

Internalizing and externalizing behaviors and their association with the treatment of adolescents with substance use disorder

Blood Oxygen Level Dependent Response and Spatial Working Memory in Adolescents With Alcohol Use Disorders

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