Conditions simulating androgenetic alopecia

Abstract

Androgenetic alopecia is a common form of hair loss, characterized by a progressive hair follicular miniaturization, caused by androgen hormones on a genetically susceptible hair follicle, in androgenic-dependent areas. Characteristic phenotype of androgenetic alopecia is also observed in many other hair disorders. These disorders are androgenetic-like diseases that cause many differential diagnosis or therapeutic error problems. The objective of this review was to systematically analyse the greatest number of conditions that mimic the AGA pattern and explain their disease pathogenesis.

Male pattern baldness and risk of incident skin cancer in a cohort of men

“…Male pattern baldness (also known as male androgenetic alopecia) is the most common cause of male hair loss, characterized by a progressive hair follicular miniaturization . Male pattern baldness is associated with higher levels of dihydrotestosterone and increased expression of androgen receptors .…”

“…Male pattern baldness (also known as male androgenetic alopecia) is the most common cause of male hair loss, characterized by a progressive hair follicular miniaturization. [1][2][3] Male pattern baldness is associated with higher levels of dihydrotestosterone and increased expression of androgen receptors. 4 The pathogenesis is generally considered as an androgen-mediated process in genetically susceptible individuals, and environmental and lifestyle risk factors are likely to be triggers.…”

“…Multivariate-adjusted analyses were performed adjusting for age (continuous variable), race/ethnicity (Caucasian, Asian, African American, or others), body mass index (<18.5, 18.5-24.9, 25-29.9, 30-34.9, or 35 kg/m 2 ), smoking (never, past, or current smokers), physical activity (in quintiles, metabolic equivalent hours/week), childhood reaction to sun (tan without burn, burn, or painful burn/blisters), times of sunburns (0, 1-2, 3-5, or 6), mole count (0, 1-2, 3-5, or 6), hair color (red, blonde, light brown, or dark brown/black), family history of melanoma (yes or no), average sun exposures of high school, age 25-35, age 36-59, and age 60 (<1, 2-5, 6-10, or 11 hr), adult life UV flux (in quintiles). An indicator variable was created for the missing value of each covariate 2. For the analysis by body sites, male pattern baldness was re-classified as three categories: no, moderate (frontal only or with mild vertex baldness), or severe baldness (frontal plus moderate to severe vertex baldness), due to power consideration.…”

“…Multivariate-adjusted analyses were performed adjusting for the same variates as listed in the footnote ofTable 2 2. For the analysis by body sites, male pattern baldness was re-classified as three categories: no, moderate (frontal only or with mild vertex baldness), or severe baldness (frontal plus moderate to severe vertex baldness), due to power consideration.…”

Typisch androgenetische Alopezie?

“…Selten können andere Haarerkrankungen das Bild einer androgenetischen Alopezie imitieren, allen voran die Alopecia areata und der Lichen planopilaris [2].…”