Abstract:Abstract. Eukaryotic genomes are packaged by the wrapping of DNA around histone octamers to form nucleosomes. Nucleosome occupancies together with their acetylation and methylation are important modification factors on all nuclear processes involving DNA. There have been recently many studies of mapping these modifications in DNA sequences and of relationship between them and various genetic activities, such as transcription, DNA repair, and DNA remodeling. However, most of these studies are experimental appro… Show more
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