Abstract:Introducción: las consecuencias de los tratamientos antineoplásicos,traen consigo implicaciones bucales y empeoramiento de otras lesiones ya prestablecidas al diagnóstico oncológico, indistintamente del órgano afectado por eltumor. Complicaciones tales como las mucositis orales, candidiasis orales, trismo,xerostomía, caries, entre otras lesiones, suelen suceder con frecuencia, y puedenser transitorias en el curso de la aplicación de terapéuticas para el cáncer, como,por ejemplo, quimioterapia y radioterapia; o… Show more
“…The National Institute for Clinical Excellence (NICE) recommends performing a specialized dental evaluation before the start of oncological treatment, with the purpose of improving oral status, through oral hygiene instructions, and elimination of infectious foci, local irritants, and defective restorations.6 The dentist's performance should be directed towards preventive measures, starting at the time of the clinical and histological diagnosis of the disease up to the completion of chemotherapy or radiotherapy treatment. 7 Dentists should be aware that the administration of antineoplastic drugs may frequently result in immediate complications at a stomatological level (erythema, mucositis, dysgeusia, glossodynia, candidiasis, herpetic gingivostomatitis, xerostomia, periodontitis and pulp necrosis). Likewise, other alterations may appear in the medium term, almost always after the third month of treatment (trismus, caries, dysphagia and dental hypersensitivity); while others manifest at a later stage (osteoradionecrosis, pain, pulpal necrosis, agenesis, enamel hypocalcification, apical root shortening, early apex closing and dilacerations).…”
Section: [ E P U B a H E A D O F P R I N T ]mentioning
Introduction: Wilms' Tumor is a malignant renal neoplasm that frequently occurs in children during the first decade of life. Clinically, it is a rapidly growing abdominal mass that causes low back pain and hematuria. Computerized axial tomography or nuclear magnetic resonance are fundamental for its diagnosis, and chemotherapy and surgery have become first-choice treatments. After diagnosis, the majority of treatment plans involve the administration of antineoplastic drugs, whose side effects may include mucositis, candidiasis, xerostomia, caries, and worsen other previously diagnosed lesions, regardless of the organ affected by the tumor. Treatment is more effective if provided by a multidisciplinary team in which the dentist plays a significant role in the implementation of an integral oral care protocol. In the present study, the management of a pediatric patient under antineoplastic treatment for Wilms' tumor is reported. Case report: A four-year-old female patient diagnosed with Wilms' tumor, who required antineoplastic treatment. She had temporary dentition with early childhood caries, irreversible pulpal lesions and agenesis of teeth 72, 82, and the germ of tooth 42. The patient received modeling based behavior management therapy, prophylactic oral hygiene, and restoration of teeth affected by caries. To present this case, the "CARE" guidelines were used. Conclusion: Poor oral health status prior to cancer therapy directly affects the quality of life and the treatment of a patient, increasing the risks of local or systemic infections. As such evaluation and dental treatment before antineoplastic therapy is important to prevent oral complications and lesions.
“…The National Institute for Clinical Excellence (NICE) recommends performing a specialized dental evaluation before the start of oncological treatment, with the purpose of improving oral status, through oral hygiene instructions, and elimination of infectious foci, local irritants, and defective restorations.6 The dentist's performance should be directed towards preventive measures, starting at the time of the clinical and histological diagnosis of the disease up to the completion of chemotherapy or radiotherapy treatment. 7 Dentists should be aware that the administration of antineoplastic drugs may frequently result in immediate complications at a stomatological level (erythema, mucositis, dysgeusia, glossodynia, candidiasis, herpetic gingivostomatitis, xerostomia, periodontitis and pulp necrosis). Likewise, other alterations may appear in the medium term, almost always after the third month of treatment (trismus, caries, dysphagia and dental hypersensitivity); while others manifest at a later stage (osteoradionecrosis, pain, pulpal necrosis, agenesis, enamel hypocalcification, apical root shortening, early apex closing and dilacerations).…”
Section: [ E P U B a H E A D O F P R I N T ]mentioning
Introduction: Wilms' Tumor is a malignant renal neoplasm that frequently occurs in children during the first decade of life. Clinically, it is a rapidly growing abdominal mass that causes low back pain and hematuria. Computerized axial tomography or nuclear magnetic resonance are fundamental for its diagnosis, and chemotherapy and surgery have become first-choice treatments. After diagnosis, the majority of treatment plans involve the administration of antineoplastic drugs, whose side effects may include mucositis, candidiasis, xerostomia, caries, and worsen other previously diagnosed lesions, regardless of the organ affected by the tumor. Treatment is more effective if provided by a multidisciplinary team in which the dentist plays a significant role in the implementation of an integral oral care protocol. In the present study, the management of a pediatric patient under antineoplastic treatment for Wilms' tumor is reported. Case report: A four-year-old female patient diagnosed with Wilms' tumor, who required antineoplastic treatment. She had temporary dentition with early childhood caries, irreversible pulpal lesions and agenesis of teeth 72, 82, and the germ of tooth 42. The patient received modeling based behavior management therapy, prophylactic oral hygiene, and restoration of teeth affected by caries. To present this case, the "CARE" guidelines were used. Conclusion: Poor oral health status prior to cancer therapy directly affects the quality of life and the treatment of a patient, increasing the risks of local or systemic infections. As such evaluation and dental treatment before antineoplastic therapy is important to prevent oral complications and lesions.
Chemotherapy and radiotherapy are aggressive treatments for cancer management. Both therapies make the stomatogatic system vulnerable to adverse effects on the oral mucosa and hard tissues. This may result in severe oral complications that can affect the quality of life of the oncologic patient. Consequently, oral diagnosis and interdisciplinary management by the stomatologist are critical for cancer treatment, regardless of its location. Objective. To determine the oral health status of cancer patients before, during and after antineoplastic treatment at a cancer institute in the city of Barranquilla, Colombia. Materials and Methods. A descriptive, longitudinal and prospective study of 131 cancer patients, was conducted. The study consisted of initial stomatological assessment of the antineoplastic therapy; classification according to the antineoplastic therapy given by the oncologist; a second stomatological assessment during treatment; and a final stomatological assessment or evaluation forty days after the end of therapy. Descriptive statistics, chi-square and MacNemar test were used to compare and identify variances at the different stages. Results. Female patients accounted for 69%, and breast cancer had 24% prevalence among the included subjects. At the initial stomatological assessment, high frequency lesions were identified, such as generalized biofilm-associated gingivitis in 69% of the cases, followed by oral candidiasis in 61%. The specific prevalence of lesions was 10.65%. In the second stomatological assessment, a greater frequency of periodontal abscesses was observed in 31%, and oral mucositis type II in 18%. The third clinical assessment showed significant changes in oral health status; an increase in the frequency of gingivitis was found in 9.9% (p<0.001); unlike before and during, there was an increment in dental caries of 26.73% (p<0.00000) at this last stage, root remains increased by 39.53% (p<0.00000), and finally, xerostomia increased by 45%. Oral candidiasis was the only lesion that showed improvement. Conclusion. An increase in the number of lesions was observed during and after antineoplastic treatment. The oral cavity is susceptible to antineoplastic treatments; gingivitis, candidiasis, xerostomia, and mucositis were observed, among others conditions.
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