Condensation of Acrylonitrile with Unsymmetrical Ketones

Synthesis of Some Substituted Piperidones

“…of tert-butanol were treated with 7 Gm. (0.13 mole) of freshly distilled acrylonitrile according to the procedure of Cason and Chang (3). Distillation yielded up to 66% of the 6-ketonitriles (Table I, Nos.…”