Concurrent Versus Simultaneous Use of Alcohol and Non-Medical Use of Prescription Drugs: Is Simultaneous Use Worse for Mental, Social, and Health Issues?

Baggio, Stéphanie; Deline, Stéphane; Studer, Joseph; N’Goran, Alexandra; Mohler‐Kuo, Meichun; Daeppen, Jean‐Bernard; Gmel, Gerhard

doi:10.1080/02791072.2014.921747

Cited by 16 publications

(12 citation statements)

References 33 publications

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“…that most polysubstance use is simultaneous (Baggio et al, 2014;McCabe et al, 2006;Quek et al, 2013;Subbaraman & Kerr, 2015). Reliable and valid measures are essential for describing substance use patterns, evaluating effectiveness of interventions, and enacting harm-prevention policies.…”

Section: Discussionmentioning

confidence: 99%

Polysubstance Use by Stimulant Users: Health Outcomes Over Three Years

Timko

Han

Woodhead

et al. 2018

J. Stud. Alcohol Drugs

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Studies show that stimulant users have varied substance use patterns and that polysubstance use is associated with poorer past or concurrent medical, mental health, and substance use outcomes. This study examined outcomes of substance use patterns prospectively. Method: A latent class analysis was conducted to examine substance use patterns among adults using stimulants (n = 710; 38.6% women) at baseline, and the health and treatment utilization outcomes of different use patterns over the subsequent 3 years. To examine associations between latent class membership and outcomes, generalized estimating equation modeling was conducted. Results: Four classes of substance use patterns at baseline were identified, involving high use of (a) methamphetamine and marijuana (23%); (b) crack cocaine and alcohol (25%); (c) powder cocaine, alcohol, and marijuana (23%); and (d) nonprescribed opioids, alcohol, marijuana, crack cocaine, and powder cocaine (i.e., polysubstance [29%]). Polysubstance class members had poorer physical health and mental health status, and more severe substance use, over the subsequent 3-year period, than other class members. Regarding treatment utilization, polysubstance class members had more medical care utilization than crack cocaine class members, and more substance use treatment utilization than powder cocaine class members. The methamphetamine, crack cocaine, and powder cocaine classes did not differ from each other on any health or treatment utilization outcome. Conclusions: People using stimulants commonly use other substances, and those whose polysubstance use includes nonprescribed opioids have especially poor health outcomes.

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Section: Discussionmentioning

confidence: 99%

Polysubstance Use by Stimulant Users: Health Outcomes Over Three Years

Timko

Han

Woodhead

et al. 2018

J. Stud. Alcohol Drugs

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“…Recent surveys have ascertained that PSU risk is particularly high among college students (Gledhill-Hoyt et al, 2000;Johnston et al, 2004;Mohler-Kuo et al, 2003;Barrett et al, 2006; National Center on Addiction and Substance Abuse at Columbia University, 2007;O'Grady et al, 2008) with alcohol, tobacco, and cannabis being the three most widely used substances in this population (Lipari and Jean-Francois, 2016). Indeed, these drugs share similar trajectories of use among emerging adults, with high rates of comorbidity (Jackson et al, 2008) and simultaneous consumption (Martin et al, 1992;Baggio et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Sex-Dimorphic Interactions of MAOA Genotype and Child Maltreatment Predispose College Students to Polysubstance Use

et al. 2020

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Polysubstance use (PSU) is highly prevalent among college students. Recent evidence indicates that PSU is based on gene x environment (G×E) interactions, yet the specific biosocial factors underlying this problem remain elusive. We recently reported that lifetime use of tobacco and cannabis in college students is influenced by the interaction of the Xlinked MAOA (monoamine oxidase A) gene and child maltreatment. Building on these premises, here we evaluated whether the same G×E interaction may also predict PSU in this population. Students of a large Midwestern university (n = 470; 50.9% females) took part in a computer survey for substance use, as well as childhood trauma exposure, using the Child Trauma Questionnaire (CTQ). DNA was extracted from their saliva samples and genotyped for MAOA variable-number of tandem repeat (VNTR) variants. Findings indicated that the highest number of substances were used by male students harboring low-activity MAOA alleles with a history of childhood emotional abuse. In contrast, female homozygous high-activity MAOA carriers with a history of emotional and physical abuse reported consumption of the greatest number of substances. Our results indicate that PSU among college students is influenced by the interaction of MAOA and child maltreatment in a sex-specific fashion. Further studies are warranted to understand the mechanisms of sex differences in the biosocial interplays underlying PSU in this at-risk group.

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“…Third, due to data limitations, we cannot distinguish between simultaneous and concurrent polydrug use. Recent research has demonstrated that simultaneous polydrug use is thought to be of greater mental, social, and health consequence compared with concurrent polydrug use (Baggio et al, 2014). Future research should examine possible differences in aggression between concurrent and simultaneous polydrug users versus monodrug users.…”

Section: Discussionmentioning

confidence: 99%

Are Polydrug Users More Physically and Verbally Aggressive? An Assessment of Aggression Among Mono- Versus Polydrug Users in a University Sample

Steele

Peralta

2017

J Interpers Violence

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Early research has revealed that patterns of aggression and antisocial behavior are present among polydrug users. Often missing from this discourse is the examination of whether polydrug users are quantitatively different from monodrug users in their use of aggression. Theoretical perspectives are often centered on the psychopharmacological effects of substance use on behavior. Consideration of possible poly- versus monodrug use differences and their impact on aggression has not been investigated. Data from this study were derived from a sample of Midwestern university students ( N = 793). The relationship between violence, aggression, and concurrent polydrug use in the last year is assessed with a series of multivariate ordinary least squares (OLS) regression models. Results demonstrate that higher incidents of physical and verbal aggression are reported among polydrug users compared to monodrug users and abstainers. When analyses were broken down by polydrug users (those who engaged in alcohol/marijuana and alcohol/NMUPD [nonmedical use of prescription drugs] stimulants), polydrug users reported higher levels of physical aggression compared to monodrug users. Similarly, monodrug users reported higher levels of physical aggression compared to nonusers. This research extends our understanding of aggression among users from two different subcategories: polydrug users in comparison to those who only engage in one form of substance use. Scholars and practitioners who work with violent offenders should consider patterns of drug use behavior when addressing substance use-related aggression.

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Concurrent Versus Simultaneous Use of Alcohol and Non-Medical Use of Prescription Drugs: Is Simultaneous Use Worse for Mental, Social, and Health Issues?

Cited by 16 publications

References 33 publications

Polysubstance Use by Stimulant Users: Health Outcomes Over Three Years

Polysubstance Use by Stimulant Users: Health Outcomes Over Three Years

Sex-Dimorphic Interactions of MAOA Genotype and Child Maltreatment Predispose College Students to Polysubstance Use

Are Polydrug Users More Physically and Verbally Aggressive? An Assessment of Aggression Among Mono- Versus Polydrug Users in a University Sample

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