Concurrent Tandem Catalysis

Wasilke, Julia‐Christina; Obrey, Stephen J.; Baker, R. Tom; Bazan, Guillermo C.

doi:10.1021/cr020018n

Cited by 1,386 publications

(457 citation statements)

References 153 publications

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“…Thus, the studied domino reaction presents a new example of competitive tandem catalysis. 10 In this study, it has been shown for the first time that alkylthioacetic aldehyde can be involved in two successive stages and appears to be active CH-acid. The Mannich ─ aza-Michael reactions sequence was only described before.…”

Section: Resultsmentioning

confidence: 74%

Unexpected one-flask synthesis of 2,4-dialkylthiopentanedials via the reaction of alkylthioacetic aldehydes with dihalomethane and diethylamine

Keiko¹,

Stepanova²,

Verochkina³

et al. 2009

Arkivoc

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The reaction of alkylthioacetic aldehydes with dihalomethane and diethylamine has allowed the unexpected domino sequence of three reactions (Mannich − dehydroamination − Michael) to be revealed. A facile one-pot three-step protocol for the synthesis of 2,4-dialkylthio pentanedials in up to 65 % yield has been developed on the basis of this reaction. A biological activity of one pentadial has been determined for the first time. The activity of alkylthioacetic aldehydes as a CH-acids is shown in two anion reactions.

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Section: Resultsmentioning

confidence: 74%

Unexpected one-flask synthesis of 2,4-dialkylthiopentanedials via the reaction of alkylthioacetic aldehydes with dihalomethane and diethylamine

Keiko¹,

Stepanova²,

Verochkina³

et al. 2009

Arkivoc

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“…The molecular weight and molecular size data for the core-shell copolymers increase with the ATRP polymerization time. (Table 1, entry [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. Again, consistent with the dendritic coreshell topology, the relative molecular weight values obtained by regular SEC are much smaller than the absolute values measured by MALS.…”

Section: Atrp With the Macro-initiatorsmentioning

confidence: 72%

“…To the best of our knowledge, this is the first example of tandem catalytic coordination/living radical polymerization for constructing polymer nanoparticles. 8,9 Our previous studies have shown that CWP provides efficient control to polymer topology. [10][11][12][13] Linear, hyperbranched, and dendritic copolymers containing a range of functionalities were obtained by CWP of simple olefinic monomers.…”

Section: Introductionmentioning

confidence: 99%

Tandem Chain Walking Polymerization and Atom Transfer Radical Polymerization for Efficient Synthesis of Dendritic Nanoparticles for Bioconjugation

et al. 2006

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A tandem chain walking polymerization (CWP) and ATRP was developed for efficient synthesis of nanoparticles for bioconjugation. Using the chain walking palladium-α-diimine catalyst (catalyst 1), dendritic polymers bearing multiple initiation sites were synthesized and used as macro-initiators for subsequent Cu(I)-mediated ATRP. Control of molecular weight and size of the water soluble core-shell polymeric nanoparticles was achieved by tuning reaction conditions. Addition of N-acryloyloxysuccinamide (NAS) monomer at the end of the ATRP afforded NHS activated polymer nanoparticles. Conjugation with both small dye molecule and protein (ovalbumin) yielded nanoparticle conjugates with relatively high dye or protein per particle ratio. With the efficient synthesis and good biocompatibility, these nanoparticles may find many potential applications in bioconjugation.

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“…6 Therefore it attracts special attention to emulate these enzymes to build functionalized molecules capable of catalyzing the polymerization reactions in a specific way to attain specified products. 7,8 Recently, considerable interest has been focused on combined catalytic systems in general chemical processes, and extensive investigations have also been drawn into their use in ethylene reactivity. 9 Respect to the preference toward iron and cobalt catalysts for use in ethylene reaction, the most common model in building the combined catalytic systems is by coupling multi-bis(imino)-pyridyl or -(imino)pyridyl metal (iron or cobalt) moieties into a molecule, 8,10,11 based on expectations that their catalytic behavior may significantly differ from those simple derivatives.…”

Section: Introductionmentioning

confidence: 99%

A Novel Al-Bridged Trinuclear Iron(II) Bis(imino)pyridyl Complex with Catalytic Ethylene Polymerization Behavior

Long¹,

Li²,

Ma³

et al. 2011

Bulletin of the Korean Chemical Society

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A self-assembled Al-bridged diiminopyridine-based ligand (3) was synthesized and characterized by FT-IR, ESI-MS and NMR spectroscopy. Electron spectral titrations were performed to confirm the formation of a novel trinuclear bis(imino)pyridyl iron(II) complex (4) upon addition of FeCl 2 into Al-bridged ligand 3 in methanol solution. Simultaneously, a typical bis(imino)pyridine-iron(II) complex (2) was synthesized and fully characterized. The X-ray crystal study of the iron(II) complex 2 disclosed a five-coordinate, distorted squarepyramidal structure with the tridentate N^N^N ligand and chlorides. The optimal molecular structure of 4 was obtained by means of molecular mechanics, which showed that each iron atom in the complex 4 is surrounded by two chlorides, a tridentate N^N^N ligand and one oxygen atom, supporting considerations about the possibility of six-coordinate geometry from MMAO or the ethylene access. A comparison of 4 with the reference 2 revealed a remarkable decrease of the catalytic activity and MMAO consumption (activity up to 0.41 × 10 3 kg mol , Al/Fe = 1600 for 2).

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Concurrent Tandem Catalysis

Cited by 1,386 publications

References 153 publications

Unexpected one-flask synthesis of 2,4-dialkylthiopentanedials via the reaction of alkylthioacetic aldehydes with dihalomethane and diethylamine

Unexpected one-flask synthesis of 2,4-dialkylthiopentanedials via the reaction of alkylthioacetic aldehydes with dihalomethane and diethylamine

Tandem Chain Walking Polymerization and Atom Transfer Radical Polymerization for Efficient Synthesis of Dendritic Nanoparticles for Bioconjugation

A Novel Al-Bridged Trinuclear Iron(II) Bis(imino)pyridyl Complex with Catalytic Ethylene Polymerization Behavior

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