Concurrent Silicosis and Pulmonary Mycosis at Death

Iossifova, Yulia; Bailey, Rachel L.; Wood, John G.; Kreiss, Kathleen

doi:10.3201/eid1602.090824

Cited by 16 publications

(21 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Siderosis generally reacts positively with Prussian blue stain which was negative in the current study. The dust particles in the present study did not resemble silicosis, which is characterized by plate-like crystals [10,14,21]. From a histological point of view, the dust accumulation observed in the lung and air sacs in this study were consistent with the appearance of coal particle depositions previously reported [13,[17][18][19].…”

Section: Discussionsupporting

confidence: 88%

“…Binder et al, [12] have suggested that dust accumulation in the lungs causing fi brosis may have a role in the appearance of pulmonary aspergillosis. Moreover, some other researchers detected concurrent pulmonary aspergillosis and pneumoconiosis in humans, and stated a similar hypothesis [14][15][16]. To our knowledge, there is no report on concurrent respiratory aspergillosis and pneumoconiosis in animals.…”

Section: Introductionsupporting

confidence: 51%

“…may easily be colonized [14,15]. Impaired immunity and inhalation of a considerable amount of spores are important risk factors in aspergillosis [1,3,14,15]. In this study, with aspergillosis fi ndings, dust particles were seen in both the lungs and the air sacs in the turkeys, and it was seen that the dust particles caused the infl ammatory reaction in the lungs and air sacs.…”

Section: Discussionmentioning

confidence: 57%

“…It has been reported that pneumoconiosis especially accompanied by pulmonary fi brosis, can disrupt the defense mechanism of the respiratory system, and thus, Aspergillus spp. may easily be colonized [14,15]. Impaired immunity and inhalation of a considerable amount of spores are important risk factors in aspergillosis [1,3,14,15].…”

Section: Discussionmentioning

confidence: 99%

“…Pneumoconiosis is also called occupational lung disease or coal workers' pneumoconiosis, is more common in humans than animals, because people work in a high risk mineral associated industry [12][13][14][15][16]. However, reports of pneumoconiosis have been described in domestic and wild mammals [17][18][19].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Concurrent Occurrence of Lower Respiratory Aspergillosis and Pneumoconiosis in a Turkey Flock

et al. 2017

View full text Add to dashboard Cite

This study describes a concurrent occurrence of lower respiratory aspergillosis and pneumoconiosis in a turkey fl ock. From one fl ock of 1000 turkeys, 4 clinically affected turkeys were examined pathologically and microbiologically. Clinically affected turkeys showed anorexia, lethargy, drooping of the wing, vomiting, dyspnea and open-beak breathing, or sudden dead. Gross lesions were observed in the air sacs and lungs which presented white to yellowish granulomas of varying size. Microscopic there was multifocal granulomatous airsacculitis and pneumonia. At the center of the granulomas, fungal hyphae were clearly highlighted in the lungs and air sacs by Gomori methenamie silver (GMS) staining. In the microbiological cultivation of the affected lungs and air sacs, Aspergillus fumigatus was isolated on Sabouraud dextrose agar. Furthermore, dark black dust accumulations were present in the cytoplasm of macrophages or interstitial tissue in the lungs and air sacs. There were also fi brosis and lymphohistiocytic cell infi ltrations around the particles. Overall, this study could implicated that pneumoconiosis might be a predisposing factor in the development of respiratory aspergillosis in turkeys.

show abstract

Section: Discussionsupporting

confidence: 88%

Section: Introductionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Concurrent Occurrence of Lower Respiratory Aspergillosis and Pneumoconiosis in a Turkey Flock

et al. 2017

View full text Add to dashboard Cite

show abstract

Reducing agate dust exposure in Khambhat, India: Protective practices, barriers, and opportunities

Falk

Bozek

Ceolin

et al. 2019

Journal of Occupational Health

View full text Add to dashboard Cite

Aims Agate workers in Khambhat, India and their community members are exposed to high levels of silica dust and related diseases. Use of effective prevention practices remains low, prompting the need for effective interventions which increase the uptake of and investment in prevention practices. We sought: (a) to describe knowledge, self‐efficacy, and practices among a population of workers, their family members, and neighbors involved in or located close to agate processing; and (b) to explore which factors are related to use of prevention practices and willingness to invest in new dust control technologies. Methods A community survey was conducted to measure demographics, occupation and financial factors, knowledge, prevention practices, barriers, risk perceptions, and efficacy beliefs. Descriptive statistics were used and, among agate workers, hierarchical logistic regression explored predictors of prevention practice use and willingness to invest. Results Among 1120 respondents, approximately 44%, 35%, and 8% of workers, family members, and neighbors used prevention practices, respectively. Knowledge and risk perceptions were generally high, where efficacy beliefs were low. Workers who had high levels of education, worked at home, and had high efficacy beliefs were more likely to report using prevention practices and being willing to invest. Barriers to prevention practice use included financial barriers, and beliefs that prevention is ineffective and health is not at risk. Conclusions Interventions and future research should be designed to engage the community to improve preventive behavior, and implement affordable and effective dust control interventions in the agate industry.

show abstract