2007
DOI: 10.1016/j.jchromb.2007.02.053
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Concurrent determination of ezetimibe and its phase-I and II metabolites by HPLC with UV detection: Quantitative application to various in vitro metabolic stability studies and for qualitative estimation in bile

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Cited by 44 publications
(29 citation statements)
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“…These included theophylline [7], ranitidine hydrochloride [9] (reported in articles concerning the HPLC-UV determination of ezetimibe), metformin hydrochloride [17], fenofibrate [18] and nitrendipine [19] (for which the reported analytical wavelengths were close to the one used in our investigation). For all the substances tested, 1 μg mL −1 methanolic solutions were prepared.…”
Section: Internal Standardmentioning
confidence: 62%
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“…These included theophylline [7], ranitidine hydrochloride [9] (reported in articles concerning the HPLC-UV determination of ezetimibe), metformin hydrochloride [17], fenofibrate [18] and nitrendipine [19] (for which the reported analytical wavelengths were close to the one used in our investigation). For all the substances tested, 1 μg mL −1 methanolic solutions were prepared.…”
Section: Internal Standardmentioning
confidence: 62%
“…The first mobile phase tested was as reported by Basha et al [7]. In a gradient sequence, the following mixture was prepared: 0.05 M aqueous formic acid solution, a mixture of water and acetonitrile 10:90 (v/v), and a mixture of water and methanol 10:90 (v/v).…”
Section: Mobile Phasementioning
confidence: 99%
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