Concordance between Different Criteria for Metabolic Syndrome in Peruvian Adults Undergoing Bariatric Surgery

Abstract

Background: Metabolic Syndrome (MetS) is a clinical entity that has been linked to several non-communicable diseases. There are various consensuses to determine its presence, such as the IDF, ALAD, Harmonized, AHA/NHLBI, NCEP-ATP III or AACE criteria. However, there is currently no standardization to properly identify it. Objective: To assess the diagnostic concordance between different criteria for MetS in Peruvian adults undergoing bariatric surgery. Methods: We conducted a secondary analysis of the institutional database of a bariatric clinic located in Lima, Peru. We obtained data from adults between 18–59 years who underwent bariatric surgery (Roux-en-Y Gastric Bypass or Sleeve Gastrectomy). According to the Kappa coefficient, a heatplot was designed to analyze the concordance of the criteria. Results: An almost perfect concordance was found between all criteria except AACE. The highest kappa coefficient (κ = 0.980) was recorded between the IDF and ALAD criteria using all the sample. Similar results were obtained when we stratified by sex. Conclusions: This study shows that, excluding the AACE, different criteria for metabolic syndrome could be used in Latino adults undergoing bariatric surgery with similar results. Given the postoperative implications, we believe that IDF and ALAD would be the best options in our population.

Association between gamma glutamyl transpeptidase to HDL-Cholesterol (GGT/HDL-C) ratio and metabolic syndrome resolution after sleeve gastrectomy

“…The diagnosis of MetS was based on the International Diabetes Federation (IDF) criteria. 13 Patients with self-perceived harmful consumption of alcohol, tobacco, and/or drugs in the last month prior to bariatric surgery, as documented in the medical history, were excluded. Additionally, patients with a history of viral hepatitis (Hepatitis B and C), autoimmune liver diseases, cholelithiasis, liver storage diseases such as hemochromatosis and hemosiderosis, a history of previous bariatric surgery, and patients who were taking medications such as amiodarone, tamoxifen, methotrexate, corticosteroids, valproate, and nitrofurantoin were also excluded.…”

“…For the sensitivity analysis, the criteria of the Latin American Diabetes Association (ALAD) were used, which varies in the central obesity values, which are: 94 cm in men and 88 cm in women. 13 Exposure. We used the GGT/HDL-C ratio to classify the study population into tertiles.…”

Comparison of metabolic syndrome prevalence and characteristics using five different definitions in China: a population-based retrospective study

“…Differences between groups for continuous and categorical variables were assessed using t -tests and x 2 tests. The kappa value (kappa ≤0.20, poor; kappa = 0.21–0.40, fair; kappa = 0.41–0.60, moderate; kappa = 0.61–0.80, substantial; kappa > 0.80, very good) was used to assess the differences and consistency between the five definitions ( 36 ). Variables potentially associated with any defined MetS were assessed using binary and multivariable logistic regression, and those with p < 0.10 were included in multivariable logistic regression.…”

Asociación entre la razón gamma glutamil transpeptidasa / colesterol-HDL (GGT/HDL-c) y resolución del síndrome metabólico en adultos sometidos a gastrectomía en manga

“…Mujeres < 80 cm), seis meses después de la intervención quirúrgica. Para el análisis de sensibilidad, se tomó como referencia los criterios de la Asociación Latinoamericana de Diabetes (ALAD) que varía en los valores de obesidad central que son: 94 cm en varones y 88 cm en mujeres (24).…”

“…Utilizamos la razón GGT/HDL-c para clasificar a la población de estudio en terciles (24). Con esto, buscamos evaluar la asociación entre esta relación y la resolución del SM en adultos que se sometieron a gastrectomía en manga.…”