“…After 16 weeks of pregnancy, any CMS is considered abnormal ( Qi et al, 2020 ). Many studies and case reports indicate that CMS is related to adverse clinical outcomes, such as premature rupture of membranes and fetal extremity deformities ( Frigo et al, 1996 ; Graf et al, 1997 ; Frigo et al, 1998 ; Wilson et al, 2003 ; Kim et al, 2007 ; Nunes et al, 2016 ; Soni et al, 2016 ; Ghose et al, 2021 ). In addition to spontaneous CMS, such separation can also occur after fetal surgery and amniocentesis ( Sydorak et al, 2002 ; Soni et al, 2016 ).…”