Concomitant solitary median maxillary central incisor and fused right mandibular incisor in primary dentition

Abstract

Solitary median maxillary central incisor (SMMCI) is a unique developmental anomaly in primary dentition. It involves central incisor tooth germs and may or may not be associated with other anomalies. Its presence, concomitant with fusion of right mandibular incisors has not previously been reported. A 5-year-old girl was presented with a single symmetrical primary maxillary incisor at the midline, with the absence of labial frenulum, an indistinct philtrum and a prominent midpalatal ridge. There was an associated fused tooth in the right incisor region and radiographic examination confirmed only one maxillary central incisor in both the dentitions. Family history revealed that the father of the girl also had a similar anomaly providing probable evidence of etiological role for heredity in SMMCI.

Solitary median maxillary central incisor in association with taurodontism and oligodontia: A case report

“…It is worth noting that about 37% of cases with SMMCI have a history of preterm birth and low birth weight 4 . Additionally, several concomitant syndromes such as ectodermal dysplasia, oromandibular limb hypogenesis syndrome type 1, and autosomal dominant holoprosencephaly, have been associated with SMMCI 1,5 . Other concurrent anomalies, including hemifacial microsomia and fused mandibular incisor in primary dentition, have also been observed along with SMMCI 3 …”

“…Solitary median maxillary central incisor (SMMCI) with an estimated incidence of 1:50000 live births, is a rare developmental disorder, and it primarily affects females. 1 , 2 This anomaly may occur as an isolated trait or as a part of SMMCI syndrome (SMMCIS), wherein midline structures of the head, such as the central incisor in the maxilla, nasal airways, frenum, incisive papilla, and palate may be affected. 2 , 3 Moreover, developmental deficiencies in midline structures of the body, including hypotelorism, microcephaly, congenital nasal malformation, cleft lip, and/or palate have also been reported.…”

Clinical Evaluation of Solitary Median Maxillary Central Incisor Syndrome

“…A large number of midline developmental defects, such as hypotelorism (closely spaced eyes) and microcephaly (small head circumference), have been reported in patients with SMMCI [2]. Sex predominance in SMMCI is a debatable issue, with some studies stating a female predominance, while others not stating any sex predilection [3, 4]. The etiology of SMMCI is unknown, but it may be related to a disruption in the development of the maxilla, which occurs during gestation at approximately 35 to 38 days, with abnormal formation of tooth germs and alveolar bone.…”