“…Moreover, it can be used in each country in the Region, the vast majority of which do not have well-consolidated cohort studies. Therefore, to say that the HEARTS app “could create differential engagement and generate digital inequity” ( 1 ) is speculative by nature. For instance, as of January 2021, South America presented a mobile connectivity rate of 103 %, as mobile internet users in the Region had multiple mobile subscriptions.…”