Conceptual Design of Distillation-Based Hybrid Separation Processes

Abstract

Hybrid separation processes combine different separation principles and constitute a promising design option for the separation of complex mixtures. Particularly, the integration of distillation with other unit operations can significantly improve the separation of close-boiling or azeotropic mixtures. Although the design of single-unit operations is well understood and supported by computational methods, the optimal design of flowsheets of hybrid separation processes is still a challenging task. The large number of operational and design degrees of freedom requires a systematic and optimization-based design approach. To this end, a structured approach, the so-called process synthesis framework, is proposed. This article reviews available computational methods for the conceptual design of distillation-based hybrid processes for the separation of liquid mixtures. Open problems are identified that must be addressed to finally establish a structured process synthesis framework for such processes.

Deterministic global optimization in conceptual process design of distillation and melt crystallization

“…The remaining, much smaller problem is then solved using more detailed models to further narrow down the search for the best design. A summary of their work in the context of conceptual design of distillation-based hybrid separation processes is presented in a recent review M a n u s c r i p t by [13]. A similar approach was also applied by Franke et al [14,15] to the design of hybrid separation processes based on distillation and melt crystallization and by Kaspereit et al [16] to the design of hybrid processes for the production of pure enantiomers.…”

Conceptual Design of Azeotropic Distillation Processes

“…Therefore, it may also be interpreted as a hybrid separation process [62,63]. Liquid phase splitting in the decanter facilitates breaking of the azeotrope to reach high purity products.…”

Design and Operation of Batch Distillation

“…For instance, the number of membrane stages and the number of modules within each stage, as well as the column stage to which the retentate/permeate is returned, must be determined. The conceptual design of continuous hybrid separations has been considered by Skiborowski et al [51], and the batch variant by Barakat and Sorensen [52].…”