Interference screws are used for graft fixation in anterior cruciate ligament reconstruction. There is current debate as to whether metal or bioabsorbable varieties provide the optimal results. This paper provides a critique of the single load-to-failure uniaxial tensile test data available in the literature, which provide the initial postoperative characteristics. Both metal and bioabsorbable screws were found to give similar levels of pull-out force and stiffness when used on similar types of graft material. Screws with bone-patellar tendon-bone grafts provided the greatest values, exceeding the forces transmitted through the native anterior cruciate ligament during normal daily activities. Hamstring grafts provided lower values, only being comparable with the forces of daily living. Consequently, this raises the question as to whether the rehabilitation regime of the hamstring patient must not be aggressive in the early postoperative stages when using either metal or bioabsorbable screws. This would ensure that the graft will not fail in the initial postoperative period before biological fixation occurs, which will then boost the strength to an acceptable level.