“…Common symptoms include difficulty rising from a seated or prone position, climbing stairs, and lifting objects due to weakness in the upper arms and thighs. LGMD can also affect other body systems, including cardiovascular and respiratory systems [ 3 ]. Variants in the dysferlin gene ( DYSF ), which encode DYSF (MIM*603,009), are associated with an autosomal recessive disorder characterized by various clinically distinct muscular dystrophies, including LGMD [ 4 ].…”