Concentrations of blood, serum and urine components in relation to number of amalgam tooth fillings in Swedish women

Abstract

Altogether 1462 women aged 38, 46, 50, 54 and 60 yr were examined in 1968/69 in a combined medical and dental population study in Gothenburg, Sweden. Number of tooth surfaces restored with amalgam fillings was assessed. The examination was repeated in 1980/81 including a new dental examination. The results from a number of biochemical analyses of blood, serum and urine were analyzed for a possible statistical relationship to number of dental amalgam fillings. As emphasis has been put in the literature on special influence from amalgam on kidney function and on the immunological system, special attention was paid to variables which might reflect these functions in our analyses. When potential confounders were taken into consideration, no significant correlations remained which seemed to be of clinical importance. Specifically, amalgam fillings were not found to be associated with impairment of the kidney function or the immunological status.

Does Inorganic Mercury Play a Role in Alzheimer's Disease? A Systematic Review and an Integrated Molecular Mechanism

“…None of these studies has taken into account the fact that most people who do not have teeth any longer at old age or who have dental repairs other than amalgam will have had amalgams in their teeth at previous times. This might explain the counterintuitive findings of some studies that many amalgam fillings correlate with better cognitive status: those with less fillings at present were likely to have had more earlier and thus have a higher likelihood of mercury accumulation in their lifetime and hence have a worse cognitive status at the time of measurements, when no fillings were present any longer, giving persons with "more amalgam fillings" a spurious benefit over those with "no or less amalgam fillings" [137,138]. Strictly speaking, such studies should not even be considered to bring clarity to the debate, since they are of doubtful methodological quality.…”

Factors associated with amalgam restorations in Taiwan

“…Finally, Taiwanese population's and dentists' knowledge of and attitudes towards dental amalgam could not be evaluated in this investigation. Results from previous studies did not show significant association between amalgam fillings and cardiovascular disease, diabetes, cancer, early death, impairment of renal or immunological function, [13][14][15] physical or mental health or memory function, 16 or Alzheimer's' disease. 17 However, dental personnel were found to have significantly higher number of central nervous symptoms 18 or less fertile (females).…”

Prenatal exposure to dental amalgam and risk of symptoms of attention‐deficit and hyperactivity disorder (ADHD)

“…23 The amount of mercury released from the amalgam fillings is correlated to the number of amalgam fillings. 24, 25 Mercury vapour is inhaled, absorbed and distributed to different body tissues 26 and is also released during setting and removing of amalgam fillings. 27…”