Computerized Volume Measurement of Brain Structure

Predictors of Relapse Following Response From a First Episode of Schizophrenia or Schizoaffective Disorder

“…Images acquired by a 3-dimensional gradient echo sequence (fast low angle shot) (coronal acquisition, 3.1-mm-thick contiguous slices, with a 256 ϫ 256 matrix in a 24-cm field of view; number of excitations = 1; repeat time = 40 milliseconds; echo time = 15 milliseconds; and flip angle = 50°) were used for morphometric analysis. 28 A semiautomated mensuration system was used for assessing whole brain, ventricular, caudate, superior temporal gyrus, and hippocampal volumes (methods described previously 16,27,29,30 ). Presence of a septum pellucidum abnormality was rated as absent, questionable, or present using previously reported methods.…”

Orbital Frontal and Amygdala Volume Reductions in Obsessive-compulsive Disorder

“…47 The anatomic regions used for measurement are illustrated elsewhere 48 and have been used in prior MRI research. 48,49 Two contiguous portions of the hippocampus-amygdala complex in each hemisphere were analyzed, which included the hippocampus and the amygdaloid complex.…”

Pituitary volume and the effects of phototherapy in patients with seasonal winter depression: a controlled study

“…Volume was estimated according to Ashtari's proposal: 21 the regions of interest of each coronal slice were outlined using a manual contouring editing function, and the area was automatically obtained by computer. Thus, the volume was calculated by adding all areas of interest in the coronal views, and by multiplying the total area by the section thickness (0.75 mm).…”