Computerised tomographic (CT) abdominal scanning in Hodgkin's disease

Earl, Helena; Sutcliffe, S B; Fry, I. Kelsey; Tucker, Audrey K.; Young, J. A.; Husband, Janet E.; Wrigley, P. F. M.; Malpas, J. S.

doi:10.1016/s0009-9260(80)80141-3

Cited by 34 publications

(9 citation statements)

References 13 publications

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“…Despite the advances in CT technology, there are still areas where CT performs less well, even when using an intravenous contrast medium. The results of Earl et al [18] show that although CT scan could occasionally demonstrate disease in nodes, its value was limited by its inability to detect involvement of nodes which were not significantly enlarged. However, CT scan would appear to be the investigation of choice in patients with suspected abdominal relapse because of the more frequent presence of disease in sites not seen on lymphography.…”

Section: Discussionmentioning

confidence: 99%

Color Doppler sonography and angioscintigraphy in hepatic Hodgkin’s lymphoma

Stojković¹,

Artiko²,

Radoman³

et al. 2009

WJG

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AIM:To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography (HRA) in secondary Hodgkin's hepatic lymphoma. METHODS:The research included patients with a diagnosis of Hodgkin's lymphoma with metastatic focal lesions in the liver and controls. Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal, hepatic and splenic veins were examined. Hepatic perfusion index (HPI) estimated by HRA was calculated. RESULTS:In the majority of patients, hepatomegaly was observed. Lesions were mostly hypoechoic and mixed, solitary or multiple. Some of the patients presented with dilated splenic veins and hepatofugal blood flow. A pulse wave was registered in the centre and at the margins of lymphoma. The average velocity of the pulse wave was higher at the margins (P > 0.05). A continuous venous wave was found only at the margins of lymphoma. There was no linear correlation between lymphoma size and velocity of pulse and continuous wave (r = 390, P < 0.01). HPI was significantly lower in patients with lymphomas than in controls (P < 0.05), pointing out increased arterial perfusion in comparison to portal perfusion. CONCLUSION:Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin's hepatic lymphoma and estimation of its intensity. Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions.

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Section: Discussionmentioning

confidence: 99%

Color Doppler sonography and angioscintigraphy in hepatic Hodgkin’s lymphoma

Stojković¹,

Artiko²,

Radoman³

et al. 2009

WJG

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“…Both have been compared prospectively with the pathological findings at laparatomy and are highly accurate (Earl et al, 1980). Lymphography has the advantages of revealing abnormalities in nodes of normal size, and permitting easy follow-up with repeat abdominal X-rays, but the disadvantage of not delineating nodes outside the para-aortic chain.…”

Section: Distribution Of Disease (Staging)mentioning

confidence: 99%

The lymphomas—current management

Lister

Malpas

1983

Postgraduate Medical Journal

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The malignant lymphomas are an heterogeneous group of diseases, manifest most frequently by the development of painless lymphadenopathy with or without splenomegaly and sometimes associated with constitutional symptoms. The natural history of these conditions is one of progressive increase in lymphadenopathy, both in terms of size and the number of sites, with death occurring from intercurrent infection or as a consequence of compression of a vital organ by lymph nodes. Spontaneous regression, although it has been reported, is very rare. The rate of progression, and the specific sites most frequently involved, vary with the specific subtype of lymphoma in question. Happily, the natural history is rarely observed nowadays since treatment is available which may cure a significant proportion of patients and be of very considerable palliative benefit to others. Their importance to the physician lies in the fact that, as a group, they are the seventh commonest malignancy in the United Kingdom, they afflict a relatively young population and have become potentially curable.

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“…from lymphocytes and histiocytes and their precursor cells. Clinically and pathologically, lymphomas are quit heterogenous.However, two distinct clinic pathologic groups are routinely distinguished; Hodgkin's disease (HD) 1,15 and Non Hodgkin's lymphoma (NHL). 4 They are one of the common neoplasms of the patients in the young age group.…”

Section: Introductionmentioning

confidence: 99%