Computer simulations of synchrony and oscillations evoked by two coherent inputs

Abstract

Coherent oscillations have been reported in multiple cortical areas. This study examines the characteristics of output spikes through computer simulations when the neural network model receives periodic/aperiodic spatiotemporal spikes with modulated/constant populational activity from two pathways. Synchronous oscillations which have the same period as the input are observed in response to periodic input patterns regardless of populational activity. The results confirm that the output frequency of synchrony is essentially determined by the period of the repeated input patterns. On the other hand, weak periodic outputs are observed when aperiodic spikes are input with modulated populational activity. In this case, higher firing rates are necessary to input for higher frequency oscillations. The spike-timing-dependent plasticity suppresses the spikes which do not contribute to the synchrony for periodic inputs. This effect corresponds to the experimental reports that learning sharpens the synchrony in the motor cortex. These results suggest that spatiotemporal spike patterns should be entrained on modulated populational activity to transmit oscillatory information effectively in the convergent pathway.

Neurodynamics of up and down transitions in a single neuron

“…Bistability is regarded as key in understanding basic phenomena of cellular functioning. The importance of bistability and the related up and down transitions has been emphasized in different fields of research (Zheng and Zhang 2013;Araki 2013;Jia and Huaguang 2012;Njap et al 2012), including spatial coherence resonance (Perc 2005(Perc , 2006Perc and Marhl 2006). The insights have also been applied to biochemical ) and calcium .…”