Abstract:Computational models and simulations can be powerful tools for gaining an insight into the extremely complex mechanisms governing tumoral growth. In order to be relied upon, however, they must be validated by comparison with sufficiently long strings of experimental or observational data. For obvious ethical reasons it is virtually impossible to obtain such data "in vivo". It may be, therefore, expedient to study the growth of tumoral lines "in vitro" or "ex vivo", i.e. by transplanting them into lab animals (… Show more
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