Computer Assisted Total Parenteral Nutrition for Pre-term and Sick Term Neonates

Skouroliakou, Maria; Konstantinou, Dimitrios; Papasarantopoulos, Petros; Matthaiou, Chrysoula

doi:10.1007/s11096-005-2462-x

Cited by 23 publications

(33 citation statements)

References 18 publications

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“…Online parenteral nutrition calculator [23][24][25][26][27][28][29][30] IV administration technology (n = 4) Auomated infusion devices [19][20][21][22] Barcoding (n = 3) Barcode medication administration system [31][32][33] Organizational (n = 16) Guidelines, policies, and procedures (n = 9)…”

Section: Intervention Type Example Of Intervention Referencesmentioning

confidence: 99%

Interventions to reduce medication errors in neonatal care: a systematic review

Nguyen

Mosel

Grzeskowiak

2017

Therapeutic Advances in Drug Safety

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Background: Medication errors represent a significant but often preventable cause of morbidity and mortality in neonates. The objective of this systematic review was to determine the effectiveness of interventions to reduce neonatal medication errors. Methods: A systematic review was undertaken of all comparative and noncomparative studies published in any language, identified from searches of PubMed and EMBASE and referencelist checking. Eligible studies were those investigating the impact of any medication safety interventions aimed at reducing medication errors in neonates in the hospital setting. Results: A total of 102 studies were identified that met the inclusion criteria, including 86 comparative and 16 noncomparative studies. Medication safety interventions were classified into six themes: technology (n = 38; e.g. electronic prescribing), organizational (n = 16; e.g. guidelines, policies, and procedures), personnel (n = 13; e.g. staff education), pharmacy (n = 9; e.g. clinical pharmacy service), hazard and risk analysis (n = 8; e.g. error detection tools), and multifactorial (n = 18; e.g. any combination of previous interventions). Significant variability was evident across all included studies, with differences in intervention strategies, trial methods, types of medication errors evaluated, and how medication errors were identified and evaluated. Most studies demonstrated an appreciable risk of bias. The vast majority of studies (>90%) demonstrated a reduction in medication errors. A similar median reduction of 50-70% in medication errors was evident across studies included within each of the identified themes, but findings varied considerably from a 16% increase in medication errors to a 100% reduction in medication errors. Conclusion: While neonatal medication errors can be reduced through multiple interventions aimed at improving the medication use process, no single intervention appeared clearly superior. Further research is required to evaluate the relative cost-effectiveness of the various medication safety interventions to facilitate decisions regarding uptake and implementation into clinical practice.

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Section: Intervention Type Example Of Intervention Referencesmentioning

confidence: 99%

Interventions to reduce medication errors in neonatal care: a systematic review

Nguyen

Mosel

Grzeskowiak

2017

Therapeutic Advances in Drug Safety

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“…Four protocols were created according to gestational age, birth weight, body weight in the beginning of the parenteral support and clinical condition (Skouroliakou et al, 2005). These were integrated into a software so that they could be used for automatic calculations, design and production of individualized PN regimens and were based on the American Society of Parenteral and Enteral Nutrition(ASPEN) guidelines (ASPEN, 1993; National Advisory Group on Standards and Practice Guidelines for Parenteral Nutrition, 1997).…”

Section: Interventionmentioning

confidence: 99%

A double-blind, randomized clinical trial of the effect of ω-3 fatty acids on the oxidative stress of preterm neonates fed through parenteral nutrition

et al. 2010

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Background/Objectives: The aim of this study was to research and draw conclusions about the effect of a parenteral nutrition (PN) fat emulsion, rich in o-3 fatty acids, on the antioxidant markers of preterm infants, when compared with a standard fat emulsion. This was a double-blind, parallel-group study conducted in Athens, Greece, using an equal randomization method. Subjects/Methods: Thirty-eight infants were selected using a double-blind method and a computer-generated randomization list. Both groups received PN, based on the same protocols. Group A received SMOFlipid fat emulsion, while group B received the standard fat emulsion (Intralipid). Serum levels of vitamin A, E and total antioxidant potential (TAP) were measured on days 0, 7 and 14 of PN support. Clinical and biochemical data were collected on days 0, 14 and on the day of discharge. Results: Serum levels of vitamin E and A were significantly increased in group A, while only vitamin A serum level was increased in group B on the fourteenth day (group A: vitamin E: P-value ¼ 0.002, vitamin A: P-value ¼ 0.000, group B: vitamin E: P-value ¼ 0.065, vitamin A: P-value ¼ 0.000). TAP was increased only in the intervention group (group A: P-value ¼ 0.000, group B: P-value ¼ 0.287). Mild anemia was developed in both groups, while no differences were detected in the infection rate, days of hospitalization, days of ventilator support and days of phototherapy. Conclusions: Oxidative stress was significantly reduced in those neonates fed with o-3 fatty acids, whereas no effect was observed in the neonates fed with standard lipids. Intervention had no effect on infants' growth and clinical outcome.

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“…Apart from miscalculations, errors may also occur when writing or typing the name of a medicine. Having a database where a doctor can select a specific chemotherapeutic agent or other supportive medications reduce the possibilities for the occurrence of errors [13][14][15][16][17][18][19] .…”

Section: The Medical History Of the Patient Is Recorded On This Formmentioning

confidence: 99%

The Development of a Software System for Patients with Breast Cancer Receiving Chemotherapy Treatment: A Pilot Study

Skouroliakou¹,

Vourvouhaki²,

Tsamis³

et al. 2013

ACRT

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Until recently, anti-cancer clinics in order to plan and schedule chemotherapy treatments applied time-consuming methods, characterized by a high risk of error occurrence. Considering all the barriers that make chemotherapy treatment and demanding procedure, to evaluate if a chemotherapy management program could improve the administration of chemotherapy treatments. The authors developed "Carci", a software tool designed to support anti-cancer clinics. The particular software program aims to provide an improved administration system for injectable anticancer agents and eliminate medication errors that could yield fatal events. The recording of patients' data, the selection of the appropriate treatment protocol, the calculations of drug dosages, the correct preparation and administration of injectable solutions and the updating of secretariat, were conducted both manually and by using the computerized method. These two methods were compared and contrasted. The use of "Carci" resulted in a decrease in the time required to calculate patients' Body Surface Area (BSA) and in a decrease in the occurrence of errors concerning the dosage of medication administered. A total of 18 patients with breast cancer were assigned to this pilot study. Significant differences were observed in BSA values (p=0.0391) and dosage (p=0.0042) between the computerized method "Carci" and manually by the doctor. Although this has been a pilot study, further evaluation of this software program in a larger sample of patients is required. Preliminary data, however, suggests that "Carci" can minimize the risk for error occurrence making chemotherapy treatment faster, easier and more accurate.

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Computer Assisted Total Parenteral Nutrition for Pre-term and Sick Term Neonates

Abstract: Use of this system can optimize pharmacists' and physicians' work and help prevent prescription and preparation errors.

Cited by 23 publications

References 18 publications

Interventions to reduce medication errors in neonatal care: a systematic review

Interventions to reduce medication errors in neonatal care: a systematic review

A double-blind, randomized clinical trial of the effect of ω-3 fatty acids on the oxidative stress of preterm neonates fed through parenteral nutrition

The Development of a Software System for Patients with Breast Cancer Receiving Chemotherapy Treatment: A Pilot Study

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