Abstract. An innovative mode of public transport(PT) service, known as customized bus(CB), has been springing up across China. This service, providing advanced, personalized and flexible demand-responsive PT, is offered to specific clientele, especially commuters. In order to resolve the problem of passenger personalized demand service and improve customer satisfaction, this paper focuses on constructing a methodology of customized bus lines and adjustment based on Soft Time Windows. Then the model is solved by the Cplex software. Taking the small-scale network as an example, different route strike of bus timetable could be obtained, and the results show that although the departure time is different, the access order is the same for the demand point. Due to the road resistance, there will be some waiting time for delay, which will guide the practical application.