Computer-assisted Management of Liquid Radioactive Waste at the University of California, San Diego

Abstract

Commercially available software has been obtained and internal software applications have been developed to implement a tracking system for liquid radioactive wastes. This system utilizes a number of data bases that maintain sampling, waste pickup and disposition information based on various parameters. Computerization has allowed access to summary information and inventory totals that are necessary for radioactive materials license compliance. Comparative reports, which are used to show trends and track historical information, can also be generated.

Gut and Brain: Investigating Physiological and Pathological Interactions Between Microbiota and Brain to Gain New Therapeutic Avenues for Brain Diseases

“…Plenty of evidence in the literature indicates gut microbiome dysfunctions in people with Parkinson’s disease ( Hamano et al, 1993 ; Clairembault et al, 2015 ; Hasegawa et al, 2015 ; Keshavarzian et al, 2015 ; Klingelhoefer and Reichmann, 2015 ; Mulak and Bonaz, 2015 ; Unger et al, 2016 ; Bedarf et al, 2017 ; Hill-Burns et al, 2017 ; Parashar and Udayabanu, 2017 ; Scheperjans et al, 2018 ; Sun and Shen, 2018 ; Breen et al, 2019 ; Santos et al, 2019 ) with changes in the microbiome composition of the upper (oral) GI tract occurring at the early stage of the disease ( Mihaila et al, 2019 ), suggesting that probiotics/psychobiotics and microbiota transplantation might be beneficial ( Dinan and Cryan, 2015 ). Apart from GI disorders, changes in the gut bacterial abundances of microbes (such as Prevotellaceae and Enterobacteriaceae ) ( Scheperjans et al, 2015 ), activation in the brain of microglial cells by short-chain fatty acids (SCFA), and intestinal flora metabolites have been reported ( Erny et al, 2015 ).…”

Clostridioides difficile and neurological disorders: New perspectives

“…GIT symptoms are common including abdominal pain, bloating, and constipation (Abbott et al, 2001 ; Fasano et al, 2015 ; Georgescu et al, 2016 ; Santos et al, 2019 ). Also, gut microbiome dysfunctions are common (Hamano et al, 1993 ; Clairembault et al, 2015 ; Hasegawa et al, 2015 ; Keshavarzian et al, 2015 ; Klingelhoefer and Reichmann, 2015 ; Mulak and Bonaz, 2015 ; Unger et al, 2016 ; Bedarf et al, 2017 ; Hill-Burns et al, 2017 ; Parashar and Udayabanu, 2017 ; Scheperjans et al, 2018 ; Sun and Shen, 2018 ; Breen et al, 2019 ; Mihaila et al, 2019 ; Santos et al, 2019 ) with changes in the gut bacterial abundances of microbes (such as Prevotellaceae and Enterobacteriaceae ) (Scheperjans et al, 2015 ), reduced content of Dorea, Bacteroides, Prevotella, Faecalibacterium, Bacteroides massiliensis, Stoquefichus massiliensis, Bacteroides coprocola, Blautia glucerasea, Dorea longicatena, Bacteroides dorei, Bacteroides plebeius, Prevotella copri, Coprococcus eutactus , and Ruminococcus callidus , and an increased content of Ruminococcus bromii, Christensenella, Catabacter, Lactobacillus, Oscillospira, Bifidobacterium, Christensenella minuta, Catabacter hongkongensis, Lactobacillus mucosae , and Papillibacter cinnamivorans (Bedarf et al, 2017 ; Petrov et al, 2017 ). Thereby, a plethora of evidence indicates that gut microbiota dysfunctions populate brain pathologies in humans.…”