Computer analysis of EEG activity in dementia of the Alzheimer's type and Huntington's disease

Extraction of spectral based measures from MEG background oscillations in Alzheimer's disease

“…In a similar sense, both EEG and MEG slowing have also been reported in other neurodegenerative diseases like mild cognitive impairment [13,36], vascular dementia [28,35,54], Lewy body dementia [18,31], major depression [34,55,56], dementia associated with Parkinson's disease [31,57,58], Pick's disease [59], Huntington's chorea [60] and progressive supranuclear palsy [31]. To extract accurate markers of AD, further studies should analyze differences in the slowing of EEG/MEG rhythms when comparing AD and the aforementioned diseases.…”

EEG low-resolution brain electromagnetic tomography (LORETA) in Huntington’s disease

“…Shista et al [20] reported a reduction of the EEG amplitude, which did not correlate with psychometric findings. However, other authors found significant correlations between increased theta and reduced alpha power and the clinical stage of dementia [16]. In another study disease duration was not correlated with any quantified EEG power measures, but the EEG of HD patients was generally characterized by a reduction in alpha and theta power and by an increase in delta and beta power [17].…”

“…In their study, increasing alterations of somatosensory evoked potentials and blink reflexes were found in the follow-up of HD patients. But routine EEGs have also been reported as abnormal [16][17][18][19][20][21][22][23][24][25]. EEG patterns differ extensively among HD patients, but the most frequent electroencephalographic abnormality described in HD is an amplitude reduction or suppression of alpha activity [16][17][18][19].…”

The utility of EEG in dementia: a clinical perspective

“…Streletz et al (1990) found increased theta and decreased alpha activity in patients with HD. However the EEG does not predict which family members will eventually develop HD, and would never approach the accuracy of gene testing.…”