Computer-aided quality assurance and certification of reference materials in the DANREF network

Trends in quality assurance of metal determination in clinical chemistry†

“…It has been suggested that the ISO guides and other guidelines (e.g., the BCR guide) 15 could be implemented in PC-programs which may be valuable tools in the certification process, in particular for small certifying bodies. 26 A PC-program specific for statistical evaluation of certified values and uncertainties on the basis of data from interlaboratory studies have been developed for that purpose. The program will generate standardized reports with full documentation of the evaluation procedure in accordance with the BCR guide.…”

“…The program will generate standardized reports with full documentation of the evaluation procedure in accordance with the BCR guide. 26…”

A DANREF Certified Reference Material for Chromate in Cement

“…Data from the intercomparison study were evaluated using the DANREF PC program. 14 This computer program is designed specifically for statistical evaluation of reference material data and documentation of the quality of reference materials in accordance with international guidelines. 14,17,18 The steps in the statistical evaluation of the intercomparison results were as follows (in brief).…”

“…14 This computer program is designed specifically for statistical evaluation of reference material data and documentation of the quality of reference materials in accordance with international guidelines. 14,17,18 The steps in the statistical evaluation of the intercomparison results were as follows (in brief). First, the goodness of fit of the laboratory mean values to a normal distribution was tested by the Kolmogorov-Smirnov-Lilliefors test.…”

“…Hence candidate certified reference materials for chromate in cement were produced within the auspices of DANREF, which is a network of Danish laboratories that produces and supports the use of certified reference materials. 14 In order to establish the certified values, an interlaboratory collaborative study was launched with the participation of 15 laboratories from seven European countries. This paper presents the results of this interlaboratory study.…”