“…Thus, researchers apply the models but find ways to account for the prediction errors by, for example, relaxing the property constraints, running a sensitivity, uncertainty, or reliability analysis. The most common indices incorporated into CAMD are health, safety, and environmental indicators, − computed using such properties like acute oral toxicity and permissible exposure limits, flammability and explosiveness, and aquatic toxicity and bioconcentration, respectively. A limited number of studies integrated also LCA indices.…”