Computer-aided joint space analysis of the metacarpal-phalangeal and proximal-interphalangeal finger joint: normative age-related and gender-specific data

Pfeil, Alexander; Böttcher, Joachim; Seidl, Bettina E.; Heyne, Jens-Peter; Petrovitch, A.; Eidner, Torsten; Mentzel, Hans‐Joachim; Wolf, Günter; Hein, Gert; Kaiser, Werner A.

doi:10.1007/s00256-007-0304-8

Cited by 36 publications

(39 citation statements)

References 33 publications

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“…Additionally, a previous study compared the joint space widths between women and men in 869 healthy subjects. The results showed that women had a significantly smaller total JSD-MCP (-11.1%) compared to men 18 . Age-related changes of joint space width.…”

Section: Discussionmentioning

confidence: 90%

“…Recent studies have evaluated finger joint space widths in healthy Caucasians measured by CAJSA; in detail continuous reductions of JSD-MCP total (-20.1%), JSD-proximal interphalangeal (PIP) total (-21.4%), and JSD-distal interphalangeal (DIP) total (-24.8%) were observed in healthy subjects between the ages of 30 years compared to 79 years [18][19][20] . Additionally, our study described age-related joint space narrowing in patients with RA.…”

Section: Rheumatologymentioning

confidence: 98%

“…Recently, normative data for the finger articulations were published, and a strong relationship between age and joint space narrowing was revealed [18][19][20] . Studies have consistently shown evidence of decreased joint space widths dependent on the severity of RA, and have demonstrated the excellent reproducibility of the MCP articulation by the CAJSA technique 15,16 .…”

mentioning

confidence: 98%

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Implementation of Z-Scores as an Age- and Sex-independent Parameter for Estimating Joint Space Widths in Rheumatoid Arthritis

Pfeil

Schäfer²,

Lehmann³

et al. 2009

J Rheumatol

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The CAJSA technique seems to distinguish age-related JSD changes in healthy volunteers from RA-induced alterations. In addition the Z-score was also able to differentiate RA-dependent narrowing of JSD. Calculation of the Z-scores based on sex- and age-specific reference data may facilitate earlier identification of patients with RA, allowing initiation of a more optimal, individually adapted therapeutic strategy.

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Section: Discussionmentioning

confidence: 90%

Section: Rheumatologymentioning

confidence: 98%

mentioning

confidence: 98%

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Implementation of Z-Scores as an Age- and Sex-independent Parameter for Estimating Joint Space Widths in Rheumatoid Arthritis

Pfeil

Schäfer²,

Lehmann³

et al. 2009

J Rheumatol

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“…In recently published studies, the excellent precision of CAJSA-parameters was veriWed with a range between 0.53 and 1.23% [16,18], indicating that joint space changes were not based on the precision error of the CAD-technique itself. The high precision of CAJSA may partly be explained by the kind of algorithm and the procedure to detect the joint edges of a bone.…”

Section: Reproducibility Of Computer-aided Joint Space Analysismentioning

confidence: 97%

“…New advances in computer-aided diagnosis (CAD) have led to signiWcant improvements in the Weld of radiogeometrical analysis of joint space widths [7], in particular for the Wnger joint space widths in patients with osteoarthritis and rheumatoid arthritis [8][9][10][11][12][13][14][15][16][17]. The computer-aided joint space analysis (CAJSA) is a recently developed CAD-technique for semiautomated measurements of joint space widths at the Wnger articulations [18].…”

Section: Introductionmentioning

confidence: 99%

Feasibility study of semi-automated measurements of finger joint space widths

et al. 2010

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The purpose of this study is to evaluate technical feasibility based on image capturing conditions (film-focus distance (FFD), film sensitivity, film brand, exposure level and tube voltage) that potentially alter radiographs and consequently may influence the semi-automated measurement of joint space distance (JSD) by computer-aided joint space analysis (CAJSA) in rheumatoid arthritis and osteoarthritis. The radiographs of a left hand (deceased man) were acquired under systematically changing image capturing conditions (exposure level: 4-8 mAs; FFD: 90-130 cm; film sensitivity: 200/400 and tube voltage: 40-52 kV with different image modalities: conventional radiographs, original digital radiographs, digital print-outs). All JSD-measurements were performed with the CAJSA-technology (Radiogrammetry Kit, Version 1.3.6; Sectra; Sweden) at the metacarpal-phalangeal articulation. JSD-analysis was not influenced by changes of FFD, exposure level, film sensitivity or film brand. JSD showed significant variation caused by tube voltage (conventional: CV = 1.913% for Agfa and CV = 2.448% for Kodak; digital: CV = 0.741% for Philips print-outs and CV = 0.620% with original digital images versus CV = 2.185% for Siemens print-outs and 0.951% with original digital images). Computer-aided joint space analysis for JSD-measurements is unaffected by the following image capturing parameters: film-focus distance, film sensitivity, film brand and exposure level. An influence of tube voltage was detected in a lesser extent for original digital images compared to the printed digital as well as conventional versions. Consequently, a standardized tube voltage is essential for accurate reproductions of CAJSA-measurements in rheumatoid arthritis and osteoarthritis.

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