Computer Aided Diagnosis System for Detection of Lung Cancer in CT Scan Images

Abstract

The automated Computer Aided Diagnosing (CAD) system is proposed in this paper for detection of lung cancer form the analysis of computed tomography images. In recent years the image processing mechanisms are used widely in several medical areas for improving earlier detection and treatment stages, in which the time factor is very important to discover the disease in the patient as possible as fast, especially in various cancer types such as the lung cancer, breast cancer. Lung cancer is the second most commonly diagnosed cancer in the United States, and it is the leading cancer related death in the world, with the current fatality rate exceeding that of the next three most common cancers (breast, prostate, and colorectal) combined. In this research, we considered the problem of developing an automated system for detecting the presence of pulmonary nodules in the lung CT .The essence of developing a system like that needed to focus on detecting nodules in their early stages, which are the very small nodules that are likely to be overlooked by the radiologists. This paper involves cancer detection system based on texture features extracted from the slice of DICOM Lung CT images for the identification of cancerous nodules. In developing this system we passed the available lung CT images and its database in basic three stages to achieve more accuracy in our experimental results: Firstly A pre-processing stage involving some image enhancement techniques helps to solve the problem. We preprocess the images (by contrast enhancement, thresholding, filtering, and blob analysis) obtained after scanning the Lung CT Images and secondly separate the suspected nodule areas (SNA) from the image by a segmentation process by using thresholding segmentation mechanism by Otsu thresholding algorithm and region growing techniques. Finally we relied on Texture features which help us to make a comparison between cancerous and non cancerous images. For accurate detection of cancerous nodules, we need to differentiate the cancerous nodules from the noncancerous. We developed an artificial neural network to differentiate them. We trained the neural network by the backpropagation algorithm and tested it with different images from a database of the DICOM CT Lung images of NIH/NCI Lung Image Database Consortium (LIDC) dataset.

CAD system: a content based image retrieval approach for pulmonary nodule detection in CT images

“…The accuracy of the system is 80%. Sharma, Disha Jindal, Gagandeep [9] proposed a system in which contrast enhancement, thresholding, filtering and blob analysis are used as preprocessing techniques. For segmenting an image, Otsu thresholding technique is used.…”

Untitled

“…NIH/NCI Lung Image Database Consortium (LIDC) public database is used in Refs. [6][7][8][9][10][11][12][13][14] to access a large number of CT Scan images. In addition to the public databases, Early Lung Cancer Action Program (ELCAP), the National Biomedical Imaging Archive (NBIA) [15][16][17], National Lung Screening Trial (NLST) [18], King Hussein Cancer Center [19], Apollo Specialty Hospitals, Chennai [20], Cornell University database [21], University of Michigan (Dept.…”

“…[30][31][32][33]. Principal component analysis (PCA) by [30], Median filtering [6][7][8]21,27], Gabor filter [6][7][8]17,27,34], multi-scale selective filter [24], Gaussian filter, average filter, and disk filter [35], Auto-enhancement algorithm and Fast Fourier transform (FFT) [17], erosion, and dilation [21], isotropic re-sampling, tri-linear interpolation [10,36], linear interpolation algorithm [25,37], contrast enhancement [11,14], thresholding, blob analysis [11], template modeling [38], adaptive thresholding [39], background thresholding [40], and mass screening and edge preserving smoothness [41] are found to be suitable for medical images. These are used to remove noise, enhance the image quality, and detect boundary of lung region to be useful for further steps.…”

An Enhanced Approach for Detection and Classification of Computed Tomography Lung Cancer

“…In [10] a computer aided diagnosing system was proposed to detect lung cancer based on texture features take out from the slice of DICOM Lung CT images. For preprocessing step K Nearest Neighbors and Weiner filters were used.…”