Computer-Aided Detection of Colorectal Polyps in CT Colonography With and Without Fecal Tagging

Mang, Thomas; Bogoni, Luca; Salganicoff, Marcos; Wolf, Matthias; Raykar, Vikas C.; Macari, Michael; Pickhardt, Perry J.; Iafrate, Franco; Laghi, Andréa; Weber, Michael; Baker, Mark E.; Ringl, Helmut; Herold, Christian; Graser, Anno

doi:10.1097/rli.0b013e31822b41e1

Cited by 20 publications

(10 citation statements)

References 29 publications

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“…23 In this study, the number of CAD strikes per patient was acceptable and in accordance with other studies. 21,24,25 We believe that the effect of stool tagging on the performance of CAD (and CTC as a whole) may be more pronounced in ultralow-dose scans, because the heterogeneity of small stool residues may be less conspicuous and small polyps may have heterogeneous structure owing to quantum mottle. On the other hand, large amounts of densely tagged fluid within the colonic lumen may contribute to artefacts much more than in standard dose scans.…”

Section: Discussionmentioning

confidence: 99%

Model-basedvshybrid iterative reconstruction technique in ultralow-dose submillisievert CT colonography

Lambert

Ouředníček²,

Jahoda³

et al. 2015

BJR

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Results: The estimated radiation dose was 0.41 6 0.05 mSv for the supine and 0.42 6 0.04 mSv for the prone acquisitions. In the endoluminal view, the image quality was rated better in HIR, whereas better scores were obtained in MBIR in the cross-sectional view, where the endoluminal noise was the lowest (p , 0.0001). Five (26%) polyps were not identified using both computeraided detection and endoluminal inspection in FBP images vs only one (5%) in MBIR and none in HIR images.Conclusion: This study showed that in submillisievert ultralow-dose CTC, the image quality for the endoluminal view is better when HIR is used, whereas MBIR yields superior images for the cross-sectional view. The inferior quality of images reconstructed with FBP may result in decreased detection of colonic lesions. Advances in knowledge: Radiation dose from CTC can be safely reduced ,1 mSv for both positions when iterative reconstruction is used. MBIR provides better image quality in the cross-sectional view and HIR in the endoluminal view.

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Section: Discussionmentioning

confidence: 99%

Model-basedvshybrid iterative reconstruction technique in ultralow-dose submillisievert CT colonography

Lambert

Ouředníček²,

Jahoda³

et al. 2015

BJR

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“…In another study, however, use of CAD as a concurrent reader decreased CT colonography interpretation time by about 3 minutes when compared with use of CAD as a secondary reader (111). Stand-alone CAD has also yielded promising results (112). In a study by another multicenter trial by Regge et al (136), CT colonography had a sensitivity of 85% for polyps 6-9 mm in diameter and a sensitivity of 91% for polyps 10 mm in diameter or larger.…”

Section: Diagnostic Sensitivity Of Ct Colonography In the Detection Omentioning

confidence: 99%

History, Evolution, and Current Status of Radiologic Imaging Tests for Colorectal Cancer Screening

Levine¹,

Yee²

2014

Radiology

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Colorectal cancer screening is thought to be an effective tool with which to reduce the mortality from colorectal cancer through early detection and removal of colonic adenomas and early colon cancers. In this article, we review the history, evolution, and current status of imaging tests of the colon-including single-contrast barium enema, double-contrast barium enema, computed tomographic (CT) colonography, and magnetic resonance (MR) colonography-for colorectal cancer screening. Despite its documented value in the detection of colonic polyps, the double-contrast barium enema has largely disappeared as a screening test because it is widely perceived as a labor-intensive, time-consuming, and technically demanding procedure. In the past decade, the barium enema has been supplanted by CT colonography as the major imaging test in colorectal cancer screening in the United States, with MR colonography emerging as another viable option in Europe. Although MR colonography does not require ionizing radiation, the radiation dose for CT colonography has decreased substantially, and regular screening with this technique has a high benefit-to-risk ratio. In recent years, CT colonography has been validated as an effective tool for use in colorectal cancer screening that is increasingly being disseminated.

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“…1c). Since it is important to detect lesions that are submerged by fluid, segmentation should include electronic cleansing of tagged fluid [3], i.e. residual fluid is eliminated by the software.…”

Section: Inside the Black Boxmentioning

confidence: 99%

CAD: How it works, how to use it, performance

Regge

Halligan

2013

European Journal of Radiology

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a b s t r a c tComputer-aided diagnosis (CAD) systems are software algorithms designed to assist radiologists (or other practitioners) in solving a diagnostic problem by using a visual prompt (or "CAD mark") to direct the observer towards potential pathology. CT colonography is a recent arrival to CAD, but could represent one of its most fruitful applications in the future. In contrast to other organs, where a variety of different pathologies are equally represented, significant colorectal pathologies other than polyps and cancer are relatively uncommon. As we shall see, this simplifies the diagnostic task for artificial intelligence developers and also for radiologists who, ultimately, must make the final decision.This review aims to present the current state-of-the-art for CAD applied to CT colonography. A brief overview of the technical essentials and of the diagnostic performance of CAD in isolation, is followed by an explanation of how CAD is used in day-to-day practice. The last section will deal with the most controversial issues affecting CAD performance in clinical practice, with a focus on the interaction between human and artificial intelligence.

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Computer-Aided Detection of Colorectal Polyps in CT Colonography With and Without Fecal Tagging

Abstract: Stand-alone CAD can be applied to both tagged and untagged CTC studies without significant performance differences. Detection rates are comparable to human readers at a relatively low false-positive rate, making CAD a useful tool in clinical practice.

Cited by 20 publications

References 29 publications

Model-basedvshybrid iterative reconstruction technique in ultralow-dose submillisievert CT colonography

Model-basedvshybrid iterative reconstruction technique in ultralow-dose submillisievert CT colonography

History, Evolution, and Current Status of Radiologic Imaging Tests for Colorectal Cancer Screening

CAD: How it works, how to use it, performance

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