Computed Tomography Versus Acute Physiology and Chronic Health Evaluation II Score in Predicting Severity of Acute Pancreatitis

Triantopoulou, Charikleia; Lytras, Dimitrios; Maniatis, Petros; Chrysovergis, Dimitrios; Manes, Konstantinos; Siafas, Ioannis; Papailiou, John; Dervenis, Christos

doi:10.1097/mpa.0b013e3180619662

Cited by 31 publications

(19 citation statements)

References 29 publications

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“…However, such indication is disputable [4,9,11,14,15,16,17,18,19,20]. At present, several prognostic indicators are available, but none being perfect [4,7,12,39].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Practice and Yield of Early CT Scan in Acute Pancreatitis: A Dutch Observational Multicenter Study

Spanier¹,

et al. 2010

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“…However, such indication is disputable [4,9,11,14,15,16,17,18,19,20]. At present, several prognostic indicators are available, but none being perfect [4,7,12,39].…”

Section: Discussionmentioning

confidence: 99%

“…a bowel perforation. However, there is no consensus whether to perform a CT in the early course of AP as a prognostic indicator [4,9,11,14,15,16,17,18,19,20,21,22,23]. Scientific proof that development of pancreatic necrosis occurs as early as within 96 h after symptom onset is disputable [15].…”

Section: Introductionmentioning

confidence: 99%

Practice and Yield of Early CT Scan in Acute Pancreatitis: A Dutch Observational Multicenter Study

Spanier¹,

et al. 2010

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“…However, MCTSI was more closely associated with patient outcome than CTSI in our study. Several studies reported a strong correlation between the CT evaluation and the clinical severity of acute pancreatitis [14,20,21] and some studies have not corroborated these findings [22][23][24].…”

Section: Correlation Of Ct Scoring Indexes With Patient Outcome Parammentioning

confidence: 99%

Modified Computed Tomography Severity Index for Evaluation of Acute Pancreatitis and its Correlation with Clinical Outcome: A Tertiary Care Hospital Based Observational Study

Banday

Gattoo

Khan

et al. 2015

JCDR

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IntrOductIOnAcute Pancreatitis is a common condition presenting as acute abdomen. This condition is broadly classified into two subtypes: one, oedematous or mild acute pancreatitis and two, a necrotizing or severe acute pancreatitis. The majority of patients have mild interstitial edematous pancreatitis (IOP) which is self-limiting. However 20% have severe acute pancreatitis (SAP) which can progress to a systemic inflammatory response syndrome (SIRS) and result in septic systemic complications with significant morbidity and mortality [1].The most common causes of pancreatitis are choledocholithiasis and ethanol abuse. Other causes include trauma, metabolic disorders (hyperlipidemia, hypercalcemia), ERCP induced pancreatitis, medications (azathioprine, sulphonamides), tumours, and congenital anomalies such as pancreas divisum [2]. Aim:To study role of modified computed tomography severity index in evaluation of acute pancreatitis and its correlation with clinical outcome. Materials and Methods:This was a hospital based prospective correlative study done on patients of all age groups referred to the Department of Radio diagnosis from the various indoor and outdoor departments of the hospital, with clinical/Laboratory/ ultrasonography findings suggestive of acute pancreatitis. The severity of pancreatitis was scored using Modified CT severity index & CT severity index and classified into mild, moderate and severe categories. Total of 50 patients of acute pancreatitis presenting to the emergency department of our hospital were included in the study. Clinical outcome parameters for correlation collected from respective referral departments included, the length of hospital stay (in days), need for surgical intervention, need for percutaneous intervention (aspiration and drainage), evidence of infection in any organ system (combination of a fever > 100°F and elevated WBC >15,000/ mm³), evidence of organ failure (PaO 2 < 60 mm Hg or need of ventilation, systolic BP of < 90 mm Hg,

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“…In another study with larger group of patients with AP, the authors concluded that CTSI was an applicable and comparable predictor of outcomes in severe pancreatitis (15). In contrast to these studies, some of the investigators argued that CTSI was not correlated with the severity of AP and was not highly important for the final patient outcome (16)(17)(18). In a study from China, the authors assessed the accuracy of CTSI, Ranson and APACHE II in patients with AP.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of CT severity index, Ranson and APACHE II and Ranson scores for clinical course and mortality in mechanically ventilated patients depend to severe pancreatitis

Adam¹,

Koçak²,

Çınar³

et al. 2017

Van Med J

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Objective:To evaluate the utility of CT severity index (CTSI) and two main scoring systems (Ranson and APACHE II) for patients underwent mechanical ventilation due to pulmonary complications associated with severe pancreatitis. Materials and Methods:Mechanical ventilated patients due to severe acute pancreatitis were enrolled the study. CTSI and two traditional clinical scoring systems including APACHE II and Ranson were used to predict the mortality rates in mechanical ventilated patients due to severe AP. Results:Nine of 36 patients were survived (25%). The ICU (Intensive Care Unit) mortality was 66.6% (n= 24) and hospital mortality was 75% (n=27). Patients had upper then 17 scores for APACHE II score, the sensitivity and specificity were 64% and 66%, respectively to predict the mortality, by CTSI (>4) and Ranson scoring system (>6) with sensitivity and specificity of 60% and 40% and 50% and 46%, respectively. Conclusion:In this study, high scores of CTSI, Ranson and APACHE II were found to be independent predictors in patients underwent mechanical ventilated due to severe pancreatitis in ICU. However, APACHE II was the most reliable and effective scoring system for predicting the mortality rate.Key Words: Acute pancreatitis, APACHE II, CT severity index, Ranson scoring system ÖZET Amaç:Şiddetli akut pankreatitte, pulmoner komplikasyonlar sıklıkla görülmektedir. Bu çalışmada, akut pankreatite bağlı gelişen pulmoner komplikasyonlar nedeniyle mekanik ventilasyon uygulanan hastalarda bilgisayarlı tomografi şiddet indeksi (CTSI) ve geleneksel iki farklı skorlama sistemi olan APACHE II ve Ranson skorlama sistemlerinin uygulanabilirliği ve güvenilirliğinin karşılaştırılması amaçlandı. Gereç ve

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Computed Tomography Versus Acute Physiology and Chronic Health Evaluation II Score in Predicting Severity of Acute Pancreatitis

Cited by 31 publications

References 29 publications

Practice and Yield of Early CT Scan in Acute Pancreatitis: A Dutch Observational Multicenter Study

Practice and Yield of Early CT Scan in Acute Pancreatitis: A Dutch Observational Multicenter Study

Modified Computed Tomography Severity Index for Evaluation of Acute Pancreatitis and its Correlation with Clinical Outcome: A Tertiary Care Hospital Based Observational Study

Evaluation of CT severity index, Ranson and APACHE II and Ranson scores for clinical course and mortality in mechanically ventilated patients depend to severe pancreatitis

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