Computed Tomography-Measured Liver Volume Predicts the Risk of Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients

Kang, Namkyu; Chung, Jung Wha; Jang, Eun Sun; Jeong, Sook‐Hyang; Kim, Jin‐Wook

doi:10.1007/s10620-020-06762-w

Cited by 3 publications

(1 citation statement)

References 49 publications

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“…The liver volume index was significantly correlated with the development of HCC. The authors then proceeded to create a nomogram incorporating age, sex, presence of cirrhosis and liver volume index which showed significantly better performance in predicting HCC development compared to traditional risk scores with AUCs of 0.758 vs. 0.661-0.712, respectively The same group utilised the liver volume index in a cohort with hepatitis C and demonstrated similar findings [116] (Supplementary Table 6) [103,[115][116][117].…”

Section: Hepatocellular Carcinoma-related Outcomesmentioning

confidence: 97%

The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review

Kutaiba,

Chung,

Goodwin

et al. 2024

Insights Imaging

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Chronic liver disease is responsible for significant morbidity and mortality worldwide. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) can fully visualise the liver and adjacent structures in the upper abdomen providing a reproducible assessment of the liver and biliary system and can detect features of portal hypertension. Subjective interpretation of CT and MRI in the assessment of liver parenchyma for early and advanced stages of fibrosis (pre-cirrhosis), as well as severity of portal hypertension, is limited. Quantitative and reproducible measurements of hepatic and splenic volumes have been shown to correlate with fibrosis staging, clinical outcomes, and mortality. In this review, we will explore the role of volumetric measurements in relation to diagnosis, assessment of severity and prediction of outcomes in chronic liver disease patients. We conclude that volumetric analysis of the liver and spleen can provide important information in such patients, has the potential to stratify patients’ stage of hepatic fibrosis and disease severity, and can provide critical prognostic information. Critical relevance statement This review highlights the role of volumetric measurements of the liver and spleen using CT and MRI in relation to diagnosis, assessment of severity, and prediction of outcomes in chronic liver disease patients. Key Points Volumetry of the liver and spleen using CT and MRI correlates with hepatic fibrosis stages and cirrhosis. Volumetric measurements correlate with chronic liver disease outcomes. Fully automated methods for volumetry are required for implementation into routine clinical practice. Graphical Abstract

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Section: Hepatocellular Carcinoma-related Outcomesmentioning

confidence: 97%

The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review

Kutaiba,

Chung,

Goodwin

et al. 2024

Insights Imaging

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Postoperative Graft Volume Reduction Is Associated With Inferior Clinical Outcomes of Superior Capsule Reconstruction Using an Acellular Dermal Matrix Allograft

Lee¹,

Shin

2024

Arthroscopy: The Journal of Arthroscopic & Related Surgery

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Effect of Medial or Lateral Graft Failure on Graft Volume and Clinical Outcomes After Superior Capsule Reconstruction for Irreparable Rotator Cuff Tears

Shin,

Lee

2024

Am J Sports Med

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Background: Graft failure is a common complication after superior capsule reconstruction (SCR). The graft in SCR is fixed on the greater tuberosity and superior glenoid, and graft failure has been reported on both sides. Purpose: To evaluate the clinical manifestations of patients with graft failure after SCR and identify the clinical and radiological differences between medial and lateral graft failure. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who underwent SCR with a dermal allograft for symptomatic irreparable rotator cuff tears between March 2018 and September 2021 were retrospectively reviewed. All patients had minimum 2-year follow-up and underwent magnetic resonance imaging at 6 months postoperatively. Patients with graft failure were divided into 2 groups: those with lateral graft failure on the greater tuberosity side (group I) and those with medial graft failure on the glenoid side (group II). Patients with intact grafts were included in group III as a control group. Intergroup differences in clinical and radiological characteristics were analyzed, and multiple regression analysis was performed. Results: Among the 93 patients included, there were 18 patients in group I, 15 in group II, and 60 in group III. Overall, 11 patients (61.1%) in group I and 9 patients (60.0%) in group II had a partial graft rupture at one anchor. The postoperative graft volume was significantly lower in group I than in groups II and III (2514.0 ± 564.3 mm3, 3183.5 ± 547.1 mm3, and 3198.0 ± 584.8 mm3, respectively; P = .002 for group I vs II; P < .001 for group I vs III). The acromiohumeral distance (AHD) was significantly increased at 6 months postoperatively compared with before surgery in group I (6.6 ± 1.6 mm vs 4.3 ± 1.9 mm, respectively; P < .001) and group II (7.4 ± 1.3 mm vs 5.7 ± 1.7 mm, respectively; P = .002). However, group I exhibited a significantly greater decrease in the AHD over time than group II ( P < .001) and a significantly lower AHD at the final follow-up than the other groups ( P < .001). The postoperative American Shoulder and Elbow Surgeons score was significantly lower in group I than in the other groups ( P < .001). On multiple regression analysis, fatty infiltration of the infraspinatus muscle, Hamada grade, and graft width were independent factors for lateral graft failure. Conclusion: Patients with lateral graft failure had inferior clinical outcomes and lower postoperative graft volumes than those with medial graft failure after SCR using a dermal allograft. The AHD of patients with lateral graft failure improved postoperatively; however, it deteriorated over time.

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Computed Tomography-Measured Liver Volume Predicts the Risk of Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients

Cited by 3 publications

References 49 publications

The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review

The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review

Postoperative Graft Volume Reduction Is Associated With Inferior Clinical Outcomes of Superior Capsule Reconstruction Using an Acellular Dermal Matrix Allograft

Effect of Medial or Lateral Graft Failure on Graft Volume and Clinical Outcomes After Superior Capsule Reconstruction for Irreparable Rotator Cuff Tears

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