Computed tomography-guided percutaneous microwave ablation for renal cell carcinoma: evaluating the performance of nephrometry scores

Efthymiou, Evgenia; Velonakis, Georgios; Charalampopoulos, Georgios; Mazioti, Argyro; Brountzos, Elias; Kelekis, Nikolaos; Filippiadis, Dimitrios

doi:10.1007/s00330-023-09774-y

Cited by 3 publications

(1 citation statement)

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“…All complications in our research emerged in lesions with a RENAL score of 9, but this was not statistically significant (p = 0.07), likely due to the limited patient sample size. Interestingly, other studies have echoed our findings, establishing a link between a higher RENAL nephrometry score and the onset of complications [18][19][20].…”

Section: Discussionsupporting

confidence: 86%

Single-Probe Percutaneous Cryoablation with Liquid Nitrogen for the Treatment of T1a Renal Tumors

Moulin,

Kammoun,

Audoual

et al. 2023

Cancers

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Kidney cancer accounts for 3% of adult malignancies and is increasingly detected through advanced imaging techniques, highlighting the need for effective treatment strategies. This retrospective study assessed the safety and efficacy of a new single-probe percutaneous cryoablation system using liquid nitrogen for treating T1a renal cancers. From May 2019 to May 2022, 25 consecutive patients from two academic hospitals, with a median age of 64.8 years [IQR 59; 75.5], underwent cryoablation for 26 T1a renal tumors. These tumors had a median size of 25.3 mm [20; 30.7] and a median RENAL nephrometry score, indicating tumor complexity, of 7 [5; 9]. No major complications arose, but three non-clinically relevant perirenal hematomas were detected on post-procedure CT scans. With a median follow-up of 795 days [573; 1020], the primary local control rate at one month stood was 80.8% (21 out of 26). The five recurrent lesions, which exhibited a higher renal score (p = 0.016), were treated again using cryoablation, achieving a secondary local control rate of 100%. No patient died, and the disease-free survival rate was 92% (23 out of 25). In conclusion, single-probe percutaneous cryoablation emerges as a promising modality for managing small renal masses. Notably, recurrence rates appear influenced by RENAL nephrometry scores, suggesting a need for further research to refine the technique.

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Section: Discussionsupporting

confidence: 86%