Computed Tomography-Guided Localization and Extended Segmentectomy for Non-Small Cell Lung Cancer

Abstract

Background: Lung cancer is one of the most devastating cancers. Low-dose computed tomography (LDCT) can detect lung cancer at an early stage of the disease when a minimally invasive surgical procedure using video-assisted thoracoscopic surgery is the best strategy. Herein, we discuss the treatment of deep lung tumors between segments or lesions located near the margin of a segment. Patients and Methods: This was a retrospective study conducted from January 2013 to January 2020 using the National Taiwan University Hospital data bank. We included early-stage non-small cell lung cancer (NSCLC) patients who underwent lung surgery and screened out those who received CT-guided localization for extended segmentectomy. Outcome measurements were safety margin, complication rate, and postoperative course. Results: During the study period, 68 patients with early-stage NSCLC received CT-guided localization followed by extended segmentectomy. The mean surgery time was 92.1 ± 30.3 min, and the mean blood loss was 32.8 mL. Mean drainage time was 2.3 ± 1 days, and the total hospital stay was 4.9 ± 1.1 days. Pathological reports showed tumor-free resection margins >2 cm. Sixty-one patients had adenocarcinoma at stage IA and two patients at stage IB. One patient had squamous cell carcinoma at stage IA. Conclusion: CT-guided localization followed by extended segmentectomy allows lung volume preservation with clean safety margins and good clinical outcomes.

Correlation between Radiological Characteristics, PET-CT and Histological Subtypes of Primary Lung Adenocarcinoma—A 102 Case Series Analysis

“…And for PET, given the increase in the number of patients from year to year, as well as the beginning of screening for this disease in some countries for risk groups, it is necessary to work in this area as much as possible to see a better radiological picture and contribute to the correlation between different morphological features on CT with pathological, immune, and genetic characteristics, as well as the characteristics that the tumor shows on other imaging methods, all with the aim of better understanding this disease. An example can be the proof that in the first stage of the disease, as well as in patients with AIS and MIA, the five-year survival is almost 100% [6,14,[19][20][21][22][23]. There were no other major studies that show gender correlation, and based on our experience, there is no predilection for any gender to develop any subtype of adenocarcinoma, so basic gender results in this paper are the consequence of a relatively small sample [24][25][26].…”

Comparison between one-stage and two-stage CT-guided localization of lung nodules with surgical resection: a single medical center experience

“…Lung cancer is the leading cause of death from cancer worldwide [ 1 ]. Low-dose chest computed tomography (CT) for surveying lung cancer is increasingly used worldwide, and many small lung nodules are detected early nowadays [ 2 , 3 ]. Most of these small pulmonary nodules are suggested to be observed and regularly followed up at outpatient departments; however, some patients may be anxious about malignant tendencies and request to undergo surgery to remove these lesions.…”

Comparison between One-Stage and Two-Stage CT-guided Localization of Lung Nodules with Surgical Resection: A Single Medical Center Experience

“…Lung cancer is the leading cause of death from cancer worldwide [1]. Low-dose chest computed tomography (CT) for surveying lung cancer is increasingly used worldwide, and many small lung nodules are detected early nowadays [2,3]. Most of these small pulmonary nodules are suggested to be observed and regularly followed up at outpatient departments; however, some patients may be anxious about malignant tendencies and request to undergo surgery to remove these lesions.…”