Computed tomography findings in canine cholangiocellular carcinoma

Tanaka, Toshiyuki; Noguchi, Shunsuke; Wada, Yusuke; Nishida, Hidetaka; Akiyoshi, Hideo

doi:10.1002/vrc2.303

Cited by 1 publication

(1 citation statement)

References 24 publications

(82 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ultrasonographic examination of two cases showed presence of multiple hyperechoic lesions and two cases showed multiple het- erogeneous or mixed echotexture lesion on ultrasonographic examination (Figure 5). Similar type of ultrasonographic findings has been reported in dogs having cholangiocellular carcinoma [25,26]. 6).…”

Section: Cholangiocellular Carcinomasupporting

confidence: 84%

Correlation of Clinicopathological and Ultrasonographic Findings for Diagnosis and Prognosis of Liver Affections in Dogs

Koundal¹,

Gupta²,

Mohindroo³

et al. 2023

Act Sci VetSci

View full text Add to dashboard Cite

The present study was undertaken on 83 dogs suffering from abdominal affections out of which 22 dogs having lesions in liver were included. Detailed history and signalment of each dog were recorded. Blood was collected from each dog for haematobiochemical analysis and ultrasonography of each dog was performed and ultrasound was done to detect lesions in liver. Ultrasonography guided FNAB and core biopsy samples were collected. Maximum incidence was recorded in Labrador retriever, male dogs and median age was recorded as 6 years in cases of liver affections. The lesions were classified as neoplastic and non-neoplastic lesions on the basis of cytology and histopathological findings. Neoplastic lesions were more common which included nine cases of hepatocellular carcinoma, four cases of cholangiocellular carcinoma, one case each of metastatic sarcoma and cystadenoma, whereas, non-neoplastic lesions included four cases of fatty change and two cases of hepatitis. Correlation between haematobiochemical alterations, cytological, histopathological and ultrasonographic findings was carried out for diagnosis and prognosis of liver affections. High correlation (95.21%), specificity (85.71%) and positive predictive value (93.8%) were observed between ultrasonographic and cytological and/ or histopathological diagnosis, whereas moderate correlation (42.86%), specificity (60%) and predictive value (60%) were observed between cytological and histopathological diagnosis of liver affections. In addition, median survival with and without censoring was recorded as 39.00 days and 109.00 days, respectively. Ultrasound guided core biopsy was found to be more effective in diagnosing liver affections as compared to ultrasound guided FNAB. From the study it was concluded that although ultrasonography can detect the lesions in liver, but for confirmation of diagnosis we need ultrasound FNAB and core biopsy.

show abstract

Section: Cholangiocellular Carcinomasupporting

confidence: 84%